Cure8 research brief
Findings describe how often and when dysplasia recurs after ESD for UC-associated neoplasia, information that can affect decisions about endoscopic treatment versus colectomy and surveillance planning.
Patients with ulcerative colitis considering or undergoing endoscopic resection for dysplasia, gastroenterologists and endoscopists who perform ESD, and clinicians planning post-ESD surveillance protocols.
This retrospective single-center series reports en bloc and R0 resection rates after ESD and measures cumulative incidence of local and metachronous dysplasia during post-ESD surveillance. The authors present recurrence rates at 1, 3, and 5 years and note that a small number of patients required colectomy for recurrent disease.
The paper suggests ESD is feasible for selected nonpolypoid UCAN when performed by experienced endoscopists and that observed recurrence patterns could help shape surveillance intervals, but the authors call for validation in larger multicenter cohorts.
Results come from a retrospective cohort at a single tertiary center with experienced endoscopists; generalizability and optimal surveillance intervals require multicenter validation.
Review the original publication for the complete reporting, methods, and context.
Funding disclosed by the source: National Research Foundation of Korea, award 2021R1A6A1A03040260; Ministry of Education, award 2021R1A6A1A03040260
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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