Cure8 trial brief
Why This Matters
IBD patients sometimes have low iron or zinc and may try supplements. This trial tested whether two phytase-containing dietary supplements are acceptable and whether they change iron and zinc absorption in adults with IBD and other chronic conditions.
Who Should Pay Attention
Adults with Crohn’s disease or ulcerative colitis in remission, clinicians advising IBD patients about supplements, and researchers interested in micronutrient absorption or phytase-containing products.
Study Snapshot
What To Know
This is a completed interventional clinical trial (NCT07380022) run by the University of Thessaly that tested two dietary supplements containing microbial phytase (Goodphyte IB Defense and Goodphyte Immunity) in adults with chronic diseases, including Crohn’s disease and ulcerative colitis. Each supplement was given as four capsules daily for two weeks.
The study’s primary aims were to assess acceptability and adherence; secondary aims included measuring changes in iron and zinc absorption and possible effects on quality of life. The trial enrolled up to 100 participants divided into two arms (50 per supplement).
Key inclusion criteria allowed adults with IBD in remission on stable medical therapy; people currently taking iron or zinc supplements, antibiotics, or other probiotic/prebiotic products were excluded.
Primary outcomes were questionnaire-based acceptability and self-reported adherence; biochemical testing of iron and zinc status was planned as a secondary outcome. This record describes study design, eligibility, interventions, and outcome measures but does not report efficacy results or safety findings.
If you’re interested in whether these supplements change iron or zinc levels or quality of life in IBD, look for a linked results posting on the trial record or a subsequent peer-reviewed publication.
Keep In Mind
This is a ClinicalTrials.gov registry record (trial-record) describing interventions and planned outcomes; no results are reported in the provided text. The study focused on acceptability/adherence and measured iron and zinc absorption as secondary outcomes.
Source Details
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.