Cure8 research brief
Phase angle, an easy-to-measure BIA parameter, was lower in IBD patients with malnutrition and higher disease activity. Detecting malnutrition earlier could matter for patients' strength, healing, and overall outcomes.
Adult IBD patients, gastroenterologists, IBD nurses, dietitians, and researchers interested in nutritional biomarkers.
This study examined 144 adult IBD outpatients using BIA, handgrip strength testing, blood tests, validated nutritional assessments and ileocolonoscopy. Lower PhA values were associated with malnutrition and with active or endoscopically worse disease. PhA correlated strongly with handgrip strength and several laboratory and body-composition markers.
PhA is a simple, noninvasive BIA parameter that could help flag patients at risk of malnutrition or higher systemic disease burden, but the study is cross-sectional and from two centers. The authors note that prospective research is needed to confirm whether PhA predicts outcomes over time or should change clinical management.
Findings are from a double-center cross-sectional study reported in an abstract/full-text summary on PubMed; the authors recommend prospective studies to establish prognostic value and external validation of the PhA cutoff.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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