Cure8 research brief
Patients with small-bowel strictures face repeat procedures or surgery; this study suggests endoscopic stricturotomy outcomes differ by whether the stricture is from Crohn’s disease and that a simple blood marker (NLR) may help predict need for repeat intervention.
Patients with small-bowel strictures (Crohn’s and non-Crohn’s), gastroenterologists who perform device-assisted enteroscopy or manage strictures, and researchers studying endoscopic therapies and biomarkers in IBD.
This study compared outcomes after balloon-assisted enteroscopy-guided endoscopic stricturotomy (ESt) for small-bowel fibrostenotic strictures caused by Crohn’s disease versus non-Crohn’s etiologies. It retrospectively reviewed 57 patients treated between 2018 and 2025 and used reintervention-free survival as the primary outcome.
Key findings reported in the abstract: non-Crohn’s strictures had higher reintervention-free survival than Crohn’s-related strictures (1-year rates ~82% vs ~55%). A baseline neutrophil-to-lymphocyte ratio (NLR) below 2.4 was associated with lower reintervention risk and remained an independent predictor in multivariable analysis.
What this means for patients: the paper suggests that endoscopic stricturotomy by balloon-assisted enteroscopy may have better longer-term results for non-CD strictures than for CD-related strictures, and that a low NLR before the procedure was linked with fewer repeat procedures.
These points summarize the abstract; the full article should be consulted for detailed methods, definitions of outcomes, and patient selection.
This is a single-center retrospective cohort with 57 patients and the source content is an abstract-level extraction. Results are associations from observational data; they do not prove causation and should be interpreted with attention to patient selection, procedural technique, and follow-up methods reported in the full paper.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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