ClinicalTrials.gov
Cure8 trial brief
Why This Matters
If simple intestinal ultrasound scores reliably match colonoscopy, IUS could offer a noninvasive, bedside tool for more frequent monitoring of ulcerative colitis activity, reducing reliance on invasive colonoscopy.
Who Should Pay Attention
Clinicians who monitor UC activity, researchers studying noninvasive disease monitoring, and adult patients with active ulcerative colitis interested in less-invasive follow-up options.
Study Snapshot
Story typeClinical Reference
Evidence typeClinical trial
Enrollment200 participants
Study statusCompleted
Source depthTrial registry record
What To Know
This clinicaltrials.gov record describes a completed observational study that compared bedside intestinal ultrasound scoring with colonoscopy (the reference standard) in adults hospitalized with active UC. The primary outcomes focus on correlation and diagnostic accuracy of simple sonographic activity scores versus colonoscopic findings at baseline.
The study notes the rationale: colonoscopy is invasive and resource-intensive, while GI ultrasound is noninvasive, bedside-capable, and potentially useful for frequent monitoring if standardized scoring proves reliable. Eligibility, exclusion criteria, and location (Assiut University, Egypt) are listed in the record.
Keep In Mind
This is a clinicaltrials.gov trial record (observational, completed) describing study design and aims; the record does not include peer-reviewed results. Interpretation requires finding the full study report or publication.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorAssiut University
Trial IDNCT07115524
Study typeObservational
Enrollment200 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedNov 5, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
Intestinal Ultrasound Guided Management in Inflammatory Bowel Disease
The study will test whether routine point‑of‑care intestinal ultrasound changes clinical decisions compared with standard monitoring, which could make monitoring less invasive and more responsive if effective.
Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
People with IBD who have no or few symptoms but still have moderate–severe inflammation on endoscopy face uncertainty about whether to switch therapies to aim for endoscopic remission.
Diagnostic accuracy of the international bowel ultrasound segmental activity score for assessing disease activity in Crohn’s disease
Standardized intestinal ultrasound scoring could help non-invasively monitor Crohn’s disease activity and reduce reliance on colonoscopy for some assessments. A high-sensitivity IUS score may be useful to rule out...