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Irish clinicians to the fore in novel Crohn’s disease studies
Two new Irish-led studies describe non-drug options that could affect how Crohn’s is treated: a dietary regimen for children that may sustain remission, and a surgical technique that may lower post-op relapse and reoperation rates.
Pediatric patients and families, adults with Crohn’s who may need surgery, gastroenterologists and colorectal surgeons, and IBD researchers.
What To Know
New Irish studies report two different approaches for Crohn’s disease: a dietary strategy for children and a surgical technique that removes the mesentery.
The first study (published in Clinical Gastroenterology and Hepatology) evaluated a regimen of two weeks of Exclusive Enteral Nutrition (EEN) followed by a Crohn’s Disease Exclusion Diet (CDED) in 56 children and found the majority maintained remission up to 24 weeks.
The second (published in Gastroenterology) tested a surgical approach that includes mesentery removal and reported lower post-operative relapse rates and reduced need for repeat operations compared with conventional surgery. The article summarizes the studies and includes comments from the researchers involved in Ireland.
It does not provide detailed methods, full data, or participant-level results in the news piece, so the findings should be read in the context of the original publications for details.
If you’re interested in the studies, look up the original articles in Clinical Gastroenterology and Hepatology and Gastroenterology for full methods and results rather than relying on this news summary.
The news article summarizes published studies but does not present full trial details, inclusion criteria, or long-term outcomes. Readers should consult the original journal publications to evaluate strength of evidence and applicability to individual patients.
