Egyptian Pediatric Association Gazette
Cure8 research brief
Why This Matters
This study describes long-term outcomes in children with IBD managed at an Egyptian tertiary centre — useful for families and clinicians to understand age at diagnosis, treatment patterns, remission and relapse rates, and risks including sepsis-related deaths.
Who Should Pay Attention
Pediatric patients with IBD, parents and caregivers, pediatric gastroenterologists, and clinicians involved in pediatric IBD care.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This retrospective single-centre cohort study from Egypt reports characteristics and long-term outcomes for 205 children with IBD diagnosed between 2010–2023. About half had ulcerative colitis and one-third had Crohn’s disease; mean age at diagnosis was 6.4 years with an average diagnostic delay of ~1.6 years.
Biologic therapy was used in 23% of patients; at last follow-up 66% were in remission, 29% had relapsing disease, and 5% had died (six deaths linked to sepsis).
The paper highlights frequent young age at onset, diagnostic delays, extensive disease at presentation, ongoing risks from relapsing disease and corticosteroid exposure, and sepsis as an important cause of mortality.
The study uses standard pediatric activity indices (PCDAI, PUCAI) and relies on chart review at a single tertiary referral centre, which may concentrate more severe cases.
This report describes outcomes in an Egyptian tertiary paediatric referral population; treatment patterns (including biologic use) and mortality related to sepsis may reflect local referral patterns, infection risks, and resource availability rather than broader population rates.
Keep In Mind
Single-centre, retrospective design and tertiary referral setting can overrepresent severe cases; diagnostic delays and infection-related mortality may be influenced by local healthcare factors. Findings are from the article abstract and extracted text.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationEgyptian Pediatric Association Gazette
PublisherSpringer Science and Business Media LLC
AuthorsHala Hassan El-Anwar Shaaban, Hala Hussien Mansour, Mohammed Ali Genena +2 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedNov 9, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
Clinical phenotypes of very early onset inflammatory bowel disease in Australian children: A single-centre retrospective study.
VEO-IBD often presents with severe, extensive disease and can include monogenic causes and early hepatobiliary complications; knowing common presentations and early management patterns helps families and clinicians plan...
Features and Outcomes of Inflammatory Bowel Disease among Filipino Children in a Tertiary Hospital: An Eleven-year Review.
This study provides region-specific pediatric IBD data from the Philippines, highlighting prevalence of very-early-onset disease, perianal involvement in Crohn's, and factors (diagnostic delay, wasting, pancolitis)...
The ‘Cross‐Trust’ Histopathology Multidisciplinary Team: Report of meeting outputs and impact on paediatric inflammatory bowel disease management in a UK tertiary centre
A cross‑trust histopathology MDT helped reclassify diagnoses in a substantial proportion of discussed paediatric IBD cases and occasionally changed management or transition planning, which could affect treatment...