Cure8 research brief
Standardised care pathways may reduce hospital admissions and help health systems manage the burden of IBD without worsening patient-reported disease control.
Clinicians, IBD programme managers, hospital administrators, researchers, and adult patients on or considering advanced therapies
The study used a prospective quasi-experimental pre/post design across multiple centres and included 1,173 patients. Outcomes came from electronic health records and validated questionnaires using the ICHOM standard set. The main analyses used difference-in-differences methods to estimate the effect attributable to the ACP.
The ACP defines a minimum standard of care aimed at reducing variation and improving coordination; after implementation, hospital admissions decreased in a way the authors attribute to the pathway, while emergency visits declined but the effect attributable to the ACP was not sustained for visits. Patient-reported disease control remained high and unchanged.
Findings come from a registered, multicentre prospective pre/post study reported in the article abstract. The quasi-experimental design can suggest associations but does not prove causation; review the full paper for detailed methods and limitations.
Review the original publication for the complete reporting, methods, and context.
Conflict statement: Competing interests: EHV received a speaker fee from Lilly outside the submitted work. CJvdW reports grants from Pfizer and Janssen and personal fees from AbbVie and Celltrion outside the submitted work. DvN has received payment or honoraria for consulting fees from Janssen, Takeda, AbbVie, Galapagos and Lilly. RLW reports personal fees from AbbVie, Janssen and Pfizer outside the submitted work. MAOV, RCAv L, JH, KR, VdJ, EK, KEV, SvdW, DvdH have nothing to disclose.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
The findings show earlier and more frequent use of imaging, endoscopic assessment, anti-TNF therapy, and seton placement for active perianal fistulizing Crohn’s disease over recent years — practices that may affect...
Nurse-led, protocolized care can make delivery of complex biologic and small-molecule IBD treatments safer and more consistent.
The findings suggest that early biologic and immunomodulator treatment may reduce the need for first surgery in Crohn's disease, which is directly relevant to treatment planning and expectations for people with IBD.
