ClinicalTrials.gov
Cure8 trial brief
Why This Matters
People with IBD and RA often try dietary changes to manage symptoms. This trial is testing two very low-carbohydrate approaches to see if they affect symptoms, quality of life, and inflammation, and whether they are feasible and safe.
Who Should Pay Attention
Adult patients with Crohn's disease or ulcerative colitis, patients with rheumatoid arthritis considering dietary therapies, clinicians advising patients on diets, and researchers studying diet–immune interactions in autoimmune disease.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment160 participants
Study statusRecruiting
Source depthTrial registry record
What To Know
This is an interventional, randomized study with three arms: ketogenic diet, carnivore (lion) diet, and a wait-list control.
Participants receive dietary guidance, remote support from medical and nutrition staff, home ketone/glucose monitoring, body-composition scales, and repeated questionnaires and laboratory tests over a 24-week intervention (after a 3-week run-in).
The study measures quality-of-life and disease-specific symptoms plus blood and stool markers related to nutrition, cardiometabolic health, and immune activation. The trial explicitly includes feasibility and safety assessments (adverse events, nutritional status, and cardiometabolic measures including blood lipids).
The wait-list group crosses over to a diet arm after 12 weeks, and some participants may voluntarily cross between diet arms with clinical approval.
Keep In Mind
This is a trial record (recruiting) and does not present results. The study explicitly plans safety and nutritional monitoring because ketogenic and carnivore diets are restrictive and can affect cardiometabolic and nutritional status.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorFuller Research Foundation
Trial IDNCT07524244
Study typeInterventional
Trial phaseNA
Enrollment160 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedOct 5, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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