ClinicalTrials.gov
Cure8 trial brief
Why This Matters
Physical activity may be a modifiable factor that could improve fitness, inflammation, symptoms like fatigue, and quality of life in children with IBD. This trial will provide objective, randomized data relevant to pediatric care.
Who Should Pay Attention
Pediatric IBD patients and their caregivers; pediatric gastroenterology clinicians; researchers studying lifestyle interventions in IBD.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment100 participants
Study statusActive_not_recruiting
Source depthTrial registry record
What To Know
This is a hospital-based interventional study testing whether a 12-week supervised physical activity program improves cardiorespiratory fitness in children and adolescents (8–17 years) with Crohn’s disease or ulcerative colitis.
The trial has three parts: observational cross-sectional and longitudinal assessments, a randomized controlled trial comparing the exercise program to usual care with cardiorespiratory fitness (20-meter shuttle run) as the primary outcome, and a 6–12 month follow-up to assess sustainability.
The study will use objective activity measurement (accelerometers), the ALPHA fitness battery, and will track inflammatory markers (fecal calprotectin, CRP), disease activity scores (PCDAI/PUCAI), musculoskeletal health, fatigue, cognition, nutritional status, and quality-of-life. A subsample will have selected biological markers analyzed.
Keep In Mind
This is a registered interventional study (trial record) describing planned methods and outcomes; it does not present trial results. Interpretive conclusions must wait for study completion and peer-reviewed publication.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorUniversidad Complutense de Madrid
Trial IDNCT07484620
Study typeInterventional
Trial phaseNA
Enrollment100 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedSep 3, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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