The Egyptian Journal of Radiology and Nuclear Medicine
Cure8 research brief
Why This Matters
IUS with the IBUS‑SAS score may offer a reliable, noninvasive way to monitor Crohn’s disease activity that correlates with clinical scores and biomarkers and aligns well with CT/MRI for most findings.
This could reduce reliance on cross-sectional imaging for routine follow-up, with caveats for perianal disease and obesity.
Who Should Pay Attention
Clinicians, radiologists, researchers, and adult patients interested in noninvasive monitoring of Crohn’s disease
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
The paper evaluated IUS as a noninvasive monitoring tool in Crohn’s disease and found high sensitivity and specificity for detecting active and moderate-to-severe disease using IBUS‑SAS cutoffs reported by the authors.
Agreement between IUS and cross-sectional imaging (CT/MRI) was substantial to almost perfect for most parameters, but perianal disease was frequently missed by IUS. This brief is grounded in the article abstract provided by the journal; Cure8 did not review the full paper beyond the supplied text.
Keep In Mind
Findings come from a small prospective cohort and are based on the supplied abstract. IUS is operator-dependent and less sensitive for perianal/deep pelvic disease; MRI remains superior there.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationThe Egyptian Journal of Radiology and Nuclear Medicine
AuthorsMohamed Khaled, Ahmed Hafez afify, Doaa M. Emara +2 more
InstitutionAlexandria University
Study typeArticle
Indexed viaOpenAlex
Source typeResearch paper
PublishedOct 16, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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