Cure8 research brief
Accurate recognition and standardized reporting of IBD-associated dysplasia help guide surveillance and surgical decisions because some dysplastic variants are flat, endoscopically invisible, and linked to advanced or synchronous neoplasia.
Gastroenterologists, GI pathologists, colorectal surgeons, IBD clinicians, and researchers focused on colorectal cancer risk in IBD
The authors review the history of classification systems and how the 6th WHO Classification of Digestive System Tumours frames IBD-associated dysplastic entities.
They highlight several morphologic variants that are often subtle, may be endoscopically invisible or flat, and can be associated with advanced or synchronous neoplasia within the same colonic segment.
The paper offers practical diagnostic criteria, a standardized reporting approach, and recommendations for handling lesions with partial features that fall short of definitive dysplasia. The review is written for pathologists and clinicians involved in IBD surveillance and emphasizes clearer terminology and reporting to guide clinical management decisions.
It does not provide new trial data or treatment recommendations.
This is a review summarizing classification changes culminating in the 6th WHO Digestive System Tumours update and discusses diagnostic challenges; it does not present new clinical trial outcomes.
Review the original publication for the complete reporting, methods, and context.
Conflict statement: Declarations. Ethics approval: Not applicable. Consent to participate: Not applicable. Competing interests: None declared.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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