A Rare Association of Turner Syndrome, Celiac Disease, and Ulcerative Colitis in a Pediatric Patient: A Case Report

What To Know

This article is a pediatric case report describing a girl with Turner syndrome who developed celiac disease in childhood and later extensive ulcerative colitis with low bone mineral density.

Initial therapies (azathioprine and 5-ASA) were complicated by pancreatitis and enzyme recurrence on re-challenge, leading to discontinuation; infliximab induction achieved sustained clinical and near-complete histologic remission.

The authors emphasize lifelong multidisciplinary surveillance for autoimmune conditions, growth, and bone health in Turner syndrome. The report is grounded in the article abstract and case details; it does not provide generalizable outcomes beyond this single patient.

Key clinical points: screening for additional autoimmune disease in Turner syndrome, monitoring growth and bone density, and a treatment course complicated by drug-induced pancreatitis requiring a biologic.

For patients and caregivers: this is a single-case illustration of complex overlapping conditions rather than evidence of typical disease course or treatment efficacy. Discuss individual risks and treatment options with your care team.