Cure8 trial brief
Persistent fatigue is a common disabling symptom in IBD even during remission; a structured adapted physical activity program could offer a non-drug way to improve daily functioning if the trial shows benefit.
Adults with IBD in remission who have persistent fatigue; IBD clinicians and allied health professionals; researchers studying supportive, nonpharmacologic interventions.
The multicenter trial plans to enroll 120 adults with Crohn's disease or ulcerative colitis in remission who report significant, persistent fatigue. Participants will be randomized to a 6-month APA program (12 one-hour sessions every two weeks plus 2 months of telephone follow-up) or usual care.
The primary outcome is change in fatigue measured by the FACIT-F score at 6 months. Secondary assessments include physical activity, quality of life, and psychological well-being.
This is a registered interventional trial based in Grenoble, France, currently NOT_YET_RECRUITING. The record describes planned design and outcomes but includes no results. Eligibility requires biochemical remission (CRP <5 mg/L, fecal calprotectin <250 µg/g) and confirmed persistent fatigue.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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