Clinical and Experimental Gastroenterology
Cure8 research brief
Why This Matters
This study suggests transgender and gender non-conforming people with IBD may face longer diagnostic delays, higher psychiatric comorbidity, and possibly more hospitalisations or surgery. That could mean gaps in care or access affecting outcomes and quality of life.
Who Should Pay Attention
TGNC adults with IBD, clinicians who care for transgender patients, IBD care teams, researchers studying health disparities, and patient advocacy groups.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This nationwide cohort study used the IBD BioResource to compare transgender and gender non-conforming (TGNC) participants with matched cisgender controls.
The abstract reports 39 TGNC respondents (mixed Crohn’s, ulcerative colitis, and unclassified IBD) and describes longer diagnostic delays, more hospitalisations and IBD-related surgery signals, and substantially higher psychiatric comorbidity (79% vs 56.8%). Quality of life impairment was substantial and similar between groups.
The paper highlights that about 31% of TGNC respondents reported gender-affirming hormone therapy and 17.9% prior gender-affirming surgery. The authors frame findings as signals that TGNC people with IBD may experience disparities in diagnostic timelines and disease control and call for larger dedicated studies.
This brief is drawn from the article abstract and BioResource cohort data as reported in the journal abstract; Cure8 has not reviewed the full study beyond the provided abstract.
Keep In Mind
Sample size for TGNC participants was small (39 respondents) and results are described as signals and trends; the authors call for larger, dedicated studies. The content here is based on the article abstract.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationClinical and Experimental Gastroenterology
AuthorsMichael Colwill, Richard Pollok, Chandni Radia +2 more
InstitutionSt George's, University of London
Study typeArticle
Indexed viaOpenAlex
Source typeResearch paper
PublishedOct 1, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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