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Genetic Testing

Genetic testing articles covering inherited risk, immune pathways, personalized medicine, and IBD research. Research context emphasizes studies, trials, biomarkers, mechanisms, and emerging IBD science.

4 articles

Clinical characteristics and prognosis of infant onset inflammatory bowel disease in Chinese children: a 10-year single-center experience.
Translational pediatrics

Clinical characteristics and prognosis of infant onset inflammatory bowel disease in Chinese children: a 10-year single-center experience.

Monogenic causes (especially IL-10RA mutations) are common in infant-onset IBD and are linked to more severe disease and higher mortality; early genetic testing and consideration of HSCT may change prognosis.

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Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features
BMC Pediatrics

Very early onset inflammatory bowel disease in Jordan: a single-center case series of clinical, genetic, and therapeutic features

VEOIBD often has a strong genetic component and different clinical needs than adult IBD; this study shows genetic findings and treatment challenges in a Middle East pediatric center, which may affect diagnosis and access...

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