Cure8 research brief
The study links residential traffic noise with higher inflammatory cytokines and worse anxiety/depression scores in people with active UC, suggesting environmental noise could be a modifiable factor affecting disease-related inflammation and quality of life.
Adults with ulcerative colitis, clinicians managing UC, and researchers studying environmental or psychosocial influences on IBD
The study included 147 adults with active UC seen at a single outpatient clinic (April 2023–April 2025). Residential traffic noise exposure was estimated from a 2022 city noise map and participants were grouped by Lden ≥55 dB versus <55 dB.
Higher noise exposure was associated with higher IL-17, IL-23, and IL-25 and with worse Self-Rating Depression and Anxiety scores; multiple regression analyses adjusted for confounders supported these associations. The authors suggest environmental stressors like traffic noise may influence inflammatory pathways and psychological well-being in UC.
Cross-sectional design prevents causal conclusions; noise was estimated from city mapping rather than individual exposure measures; full methods and potential confounders should be reviewed in the complete article.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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