ClinicalTrials.gov
Cure8 trial brief
Why This Matters
A multimodal program combining exercise, diet, and psychological support could offer practical, nonpharmacologic ways to improve fitness, quality of life, and potentially treatment outcomes in people with ulcerative colitis — but feasibility and effects need testing.
Who Should Pay Attention
Adult patients with ulcerative colitis interested in lifestyle and self-management approaches; IBD clinicians and allied health providers (dietitians, physiotherapists, psychologists); researchers studying interventions to improve IBD outcomes.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment30 participants
Study statusCompleted
Source depthTrial registry record
What To Know
This is a completed interventional pilot study registered at ClinicalTrials.gov (NCT05743153) conducted in Nijmegen, Netherlands, that enrolled adults (≥18) with ulcerative colitis.
The intervention combined home-based endurance and resistance training videos (plus daily low-intensity activity), diet counseling aiming for higher protein/energy intake and a mainly plant-based diet with avoidance of red/processed meats and sweetened drinks, and psychological screening with referral as needed.
The primary goal was feasibility (accrual, attrition, adherence) over 24 weeks; secondary measures included individual-level changes (fitness, nutrition, mental health, QoL, work productivity) and therapy-related outcomes (adherence, adverse events, corticosteroid use, biochemical/clinical response or remission, and PROMs). Planned enrollment was 30.
Keep In Mind
This is a ClinicalTrials.gov trial record (NCT05743153) describing a completed pilot interventional study focused on feasibility and multiple secondary outcomes. The registry entry does not include trial results; look for a linked publication or results posting for outcomes.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorRadboud University Medical Center
Trial IDNCT05743153
Study typeInterventional
Trial phaseNA
Enrollment30 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedSep 22, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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