Alimentary pharmacology & therapeutics
Cure8 research brief
Why This Matters
If you have IBD — especially Crohn’s — this study suggests your long-term risk of needing dialysis or a kidney transplant may be higher than the general population. Certain treatments and prior bowel surgery were linked to higher risk, so kidney health may warrant attention during follow-up.
Who Should Pay Attention
Adults with IBD (particularly Crohn’s), clinicians who manage IBD and comorbid conditions, nephrologists, and researchers studying IBD complications.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
The study used administrative data from 1984–2023 comparing 12,639 IBD patients to 126,180 controls and defined ESRD by outpatient dialysis claims. The authors report IBD was an independent predictor of ESRD (about 1.5-fold higher risk overall), with a larger effect in Crohn’s disease.
Reported predictors within IBD included oral steroid exposure, allopurinol use, and prior bowel surgery — findings that the authors suggest support closer renal monitoring in higher-risk patients.
Keep In Mind
Structured-content depth: abstract. This summary is grounded in the article abstract and administrative-database methods; it does not represent a full-text review. Observational data show associations, not causation. SummaryConfidence: medium.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationAlimentary pharmacology & therapeutics
AuthorsOnuma Sattayalertyanyong, Zoann Nugent, Bryce Barr +2 more
InstitutionDivision of Gastroenterology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Study typeJournal article
Indexed viaPubMed
Source typeResearch paper
PublishedJul 14, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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