ClinicalTrials.gov
Cure8 trial brief
Why This Matters
Diet is a potentially modifiable factor that could affect symptoms, inflammation, and the gut microbiome in ulcerative colitis; this trial aims to test whether a modified Mediterranean diet added to standard therapy improves both symptoms and objective inflammation markers.
Who Should Pay Attention
Adults with ulcerative colitis, clinicians (gastroenterologists, nutritionists), and researchers focused on diet–microbiome interactions.
Study Snapshot
Story typeClinical Reference
Trial phaseNA
Enrollment62 participants
Study statusNot_yet_recruiting
Source depthTrial registry record
What To Know
This is a registered, not-yet-recruiting randomized interventional trial testing a modified Mediterranean diet (reduced carbohydrates) for 12 weeks alongside standard therapy in people with ulcerative colitis.
The study will compare the diet intervention group (guided by a nutritionist) with a control group following standard dietary recommendations and will assess symptoms plus objective inflammation markers, including fecal calprotectin, CRP, endoscopy, intestinal ultrasound, and serum galectin-3 as a biomarker.
The trial record emphasizes that prior Mediterranean-diet studies in UC have been small or retrospective and often lacked objective inflammatory measures; this study aims to fill that gap with prospective randomized design and biomarker/imaging outcomes.
If you’re interested in diet-based approaches to managing UC, this trial is designed to provide more rigorous evidence about whether a modified Mediterranean diet can improve symptoms and inflammation when added to standard care.
Keep In Mind
Registered as an interventional randomized trial and currently not yet recruiting; this record describes planned methods and outcomes rather than study results.
Source Details
Review the original publication for the complete reporting, methods, and context.
Clinical trial
Evidence type derived from source or registry metadata.
PublicationClinicalTrials.gov
SponsorUniversity Hospital Sestre Milosrdnice
Trial IDNCT07857447
Study typeInterventional
Trial phaseNA
Enrollment62 participants
Indexed viaClinicalTrials.gov
Source typeTrial registry record
PublishedOct 5, 2026, 12:00 AM
Content availableTrial registry record
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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