Inflammatory Bowel Diseases
Cure8 research brief
Why This Matters
Bowel urgency is a common symptom that may predict higher risk of treatment escalation, hospitalization, or surgery in UC even when bleeding and stool frequency look controlled. Better assessment of urgency in clinic could improve risk detection and management.
Who Should Pay Attention
Adult patients with ulcerative colitis, IBD clinicians, and researchers studying symptoms, biomarkers, and outcomes in UC.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
The study used a retrospective cohort from a single IBD clinic in Calgary and analyzed symptom reporting, endoscopy, and fecal calprotectin alongside clinical outcomes. Urgency was usually recorded as present/absent rather than graded, and some patients had ongoing urgency despite normalized bleeding and stool frequency.
In adjusted models urgency was associated with a roughly 2.6-fold increased hazard of a subsequent UC-related event. Clinical takeaway: Urgency appears to provide incremental information about disease activity beyond bleeding and stool frequency and may help identify patients at higher near-term risk of treatment escalation, hospitalization, or surgery.
The study highlights that urgency is inconsistently assessed and usually captured in a binary way in routine care. Methods/context note: This brief is based on the article abstract provided by the journal (structured content depth: abstract).
IBD Clinic patients with index visits during Dec 2022–May 2023 were included; details are from the source abstract and not a full protocol review.
Keep In Mind
This is a retrospective cohort from a single center and the summary is grounded in the article abstract. Urgency was mainly recorded as present/absent and the findings reflect associations, not proven causation.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationInflammatory Bowel Diseases
PublisherOxford University Press (OUP)
AuthorsPriyanka K Gill, Holly Finch, Levi Stein +12 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedJul 17, 2026, 12:00 AM
Content availableJournal abstract
Funding disclosed by the source: Eli Lilly and Company
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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