ACG case reports journal
Cure8 research brief
Why This Matters
Inflammation can hide colorectal neoplasia on initial colonoscopy, so repeat colonoscopic assessment after remission induction may detect lesions missed during active disease—important for elderly-onset UC where sporadic cancer can occur.
Who Should Pay Attention
Adults with ulcerative colitis (especially elderly-onset), gastroenterologists, and clinicians involved in IBD surveillance
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
Active inflammation can obscure underlying colorectal neoplasia on colonoscopy; reassessment after inflammation has settled may uncover lesions that were previously hidden. In this report the tumor showed p53 overexpression limited to the lesion and no dysplasia in surrounding mucosa, features the authors interpret as more consistent with a sporadic cancer.
The case supports close endoscopic surveillance and consideration of repeat colonoscopy after remission induction in elderly-onset UC.
Keep In Mind
This is an abstract of a single case report in ACG Case Reports Journal. Case reports can highlight possibilities but cannot define how common a finding is or change guidelines by themselves.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationACG case reports journal
AuthorsTomotaka Tanaka, Yoshikazu Yoshifuku, Hajime Teshima +7 more
InstitutionDepartment of Gastroenterology, JA Hiroshima General Hospital, Hiroshima, Japan.
Study typeCase reports, journal article
Indexed viaPubMed
Source typeResearch paper
PublishedOct 26, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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