Cure8 research brief
Enteric hyperoxaluria increases risk of calcium oxalate kidney stones and kidney injury. Knowing how common EH is in Crohn's disease and after bariatric surgery helps identify who might benefit from screening and preventive measures.
Adults with Crohn's disease (especially post-ileal resection or with steatorrhea), clinicians treating IBD or post-bariatric-surgery patients, nephrologists, and researchers focused on oxalate-related kidney disease.
This review searched PubMed and Embase and pooled prevalence using standard meta-analytic methods; heterogeneity across studies was very high and the authors emphasize that whether an oxalate load was given before urine collection strongly affects measured prevalence (about 39% without provocation vs ~65–74% with provocation).
Among Crohn's disease patients, ileal resection and presence of steatorrhea were associated with higher rates of EH, which helps identify who may need screening.
This record is a preprint systematic review; heterogeneity across included studies was high and many did not report whether urine was collected after an oxalate load, which strongly influences measured prevalence. Interpret pooled estimates cautiously.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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