Cure8

Why This Matters

Stoma creation and whether it can later be closed greatly affects daily life and planning for people with Crohn's disease.

Knowing which indications most often lead to permanent stomas (notably anorectal disease) can inform discussions with surgeons and gastroenterologists about timing, goals, and expectations of surgery.

Who Should Pay Attention

Adult patients with Crohn's disease (especially those facing stoma surgery), post-surgery patients, colorectal surgeons, gastroenterologists, and caregivers involved in surgical decision-making.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

The study reviewed 422 adult Crohn's patients who had stomas created between 1974 and 2017. At initial creation, 25% were permanent stomas and 75% temporary. Among temporary stomas, only 31% were closed; 27% became permanent and 42% remained unclosed at last follow-up.

Anorectal disease was the leading indication and had the lowest closure rate (13%), while stomas created for poor bowel condition had higher closure rates (56%). Permanent stoma-free survival at 10 and 20 years was reported (≈95% and 83% overall; slightly higher in patients treated after 2005).

What to watch for: The paper highlights that anorectal involvement in Crohn's disease is strongly associated with low stoma-closure rates, so preventing or controlling anorectal disease may reduce the need for permanent stomas.

Keep In Mind

This is a retrospective single-center cohort spanning many decades (1974–2017). Surgical techniques, medical therapy, and perioperative care have changed over that period; the authors note improved permanent stoma-free survival for patients treated after 2005. Results reflect the center's experience and indications (high proportion of anorectal disease).

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationAnnals of gastroenterological surgery
AuthorsNagano K, Kuwahara R, Tomoo Y +7 more
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedApr 6, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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