Surgical endoscopy
Cure8 research brief
Why This Matters
Findings help patients and surgical teams set expectations before laparoscopic ileocecal resection: certain disease patterns (fistulizing) and older age raise the chance of conversion, which can increase length of stay and medical complications but not major surgical complication rates in this study.
Who Should Pay Attention
Surgeons and surgical teams; adult patients with Crohn’s disease considering or scheduled for laparoscopic ileocecal resection; caregivers and clinicians planning perioperative care; researchers studying surgical outcomes in IBD.
Study Snapshot
Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract
What To Know
This study reviewed a tertiary-center cohort of adults having elective laparoscopic ileocecal resection for Crohn’s disease (2011–2025) to identify preoperative predictors of conversion to open surgery and to compare postoperative outcomes.
Using LASSO-penalized multivariable regression, the authors found older age and fistulizing disease behavior were independent predictors of conversion, while a stenotic phenotype was associated with lower conversion risk. About 15.7% of planned laparoscopic cases required conversion.
Conversion was linked to longer hospital stays and higher rates of medical (non-major surgical) complications, but not to higher rates of major surgical complications or reoperation.
Takeaway: conversion appears more likely with older patients and fistulizing disease, and although it raises some medical morbidity and length of stay, it did not increase major surgical complications in this cohort. This supports viewing conversion as a reasonable intraoperative decision in complex cases rather than solely as a technical failure.
Keep In Mind
This is a retrospective, single-center cohort using LASSO regression to identify predictors; results show associations, not causal proof. Definitions of “fistulizing” and “stenotic” behavior and specific perioperative protocols may differ between centers, which can affect generalizability.
Source Details
Review the original publication for the complete reporting, methods, and context.
Research paper
Evidence type derived from source or registry metadata.
PublicationSurgical endoscopy
AuthorsViolante T, Cardelli S, Calini G +6 more
Study typeJournal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedJul 20, 2026, 12:00 AM
Content availableJournal abstract
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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