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Self-expandable metal stents versus endoscopic balloon dilatation for the treatment of strictures in Crohn's disease: a retrospective long-term follow-up of the ProtDilat study, an open label, multicenter, randomized trial.
Journal of Crohn's & colitis

Cure8 research brief

Self-expandable metal stents versus endoscopic balloon dilatation for the treatment of strictures in Crohn's disease: a retrospective long-term follow-up of the ProtDilat study, an open label, multicenter, randomized trial.

1 min read
Procedures and surgery Stricture Clinical study Adult patients Clinicians Researchers Patients On Biologics Crohn's disease

Why This Matters

Long-term results suggest endoscopic approaches—especially balloon dilatation—help many people with Crohn’s strictures avoid surgery and have fewer severe complications compared with surgical treatment.

Who Should Pay Attention

Adults with Crohn's disease and symptomatic intestinal strictures; gastroenterologists and endoscopists; researchers in stricture management

Study Snapshot

Story typeResearch paper
Evidence typeClinical trial
Source depthJournal abstract

What To Know

This report follows 80 ProtDilat participants for a median of ~7 years. Overall, ~31.5% needed surgery during follow-up; EBD, stable medical therapy (no intensification), and having a single endoscopic treatment were associated with lower surgery risk.

Among patients successfully treated endoscopically at the start, a substantial proportion remained free of both surgery and further endoscopic retreatment long-term. Surgical interventions had a higher rate and greater severity of adverse events than endoscopic care.

Keep In Mind

This summary is grounded in the article abstract (structured content depth: abstract). The full article includes more detail on patient selection, stricture features, and procedural specifics that affect applicability.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Clinical trial Evidence type derived from source or registry metadata.
PublicationJournal of Crohn's & colitis
AuthorsLoras C, Ruiz-Ramírez P, Gornals JB +22 more
Study typeComparative study, multicenter study, randomized controlled trial, journal article
Indexed viaEurope PMC
Source typeResearch paper
PublishedSep 1, 2026, 12:00 AM
Content availableJournal abstract

Funding disclosed by the source: Taewoong; Catalan Society of Gastroenterology; Foundation of Spanish Society of Digestive Endoscopy; Spanish National Institute of Health

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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