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Why This Matters

Delays and incomplete pre-referral screening are common in pediatric IBD and can affect how sick children are when they first see specialists. Better, standardized use of fecal calprotectin and abdominal ultrasound before referral might shorten delays and improve early care.

Who Should Pay Attention

Pediatric gastroenterologists, primary care clinicians and pediatricians who evaluate children with possible IBD, parents and caregivers of children with persistent GI symptoms, and health systems designing referral pathways.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

The authors classified diagnostic pathways as appropriate, partially appropriate, or inappropriate based on referral trajectory and whether fecal calprotectin (FC) and/or abdominal ultrasound (AUS) were done before referral. Most pathways were rated inappropriate (60.9%); only 17.2% were deemed appropriate.

FC was done pre-referral in ~60% of patients and AUS in ~42%; both were done together in ~33%. Shorter diagnostic delay was linked to acute severe colitis, hematochezia, fever, and weight loss, while severe intestinal presentations made appropriate investigations more likely.

Systemic or extraintestinal signs (for example oral aphthosis) were more often associated with inappropriate pathways. The authors conclude that standardized screening and referral protocols (including FC and AUS) before referral may improve timeliness and early management of pediatric IBD.

Keep In Mind

This is a retrospective, single-center study from Italy covering diagnoses from 2015–2025; findings describe associations not proven causation. The structured content is based on the article abstract.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationJournal of pediatric gastroenterology and nutrition
AuthorsFrancesca Borgiani, Mario Brusco, Elisa Franceschini +2 more
InstitutionDepartment of Pediatrics, Polytechnic University of Marche, Ancona, Italy.
Study typeJournal article
Indexed viaPubMed
Source typeResearch paper
PublishedSep 21, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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