Cure8
High prevalence of fatigue in patients with inflammatory bowel disease: association with physical activity intensity and sedentary behavior
Frontiers in Public Health

Cure8 research brief

High prevalence of fatigue in patients with inflammatory bowel disease: association with physical activity intensity and sedentary behavior

2 min read
Symptoms and flares Fatigue Depression Anxiety Clinical study Adult patients Clinicians Newly Diagnosed

Why This Matters

Fatigue is very common in people with IBD—even when the disease is in remission—and is linked with lower physical activity, more sitting time, and with anxiety/depression. Understanding these links may help patients and clinicians focus on activity and mental health as part of fatigue management.

Who Should Pay Attention

Adult IBD patients (Crohn’s and ulcerative colitis), IBD clinicians and nurses, and those interested in lifestyle approaches to symptom management.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

High prevalence of fatigue was reported in a cross-sectional study of 422 IBD patients (64.5% Crohn’s disease, 35.5% colitis) attending a hospital day unit. Most participants were in clinical remission.

Fatigue affected about 70% of patients (mostly mild), was associated with higher rates of self-reported depression and anxiety, and correlated with lower total physical activity—especially low participation in high-intensity exercise—and longer daily sitting time. The study also noted associations between fatigue and use of supplements and food avoidance.

This report is based on the article abstract and extracted text from Frontiers in Public Health. It describes a descriptive, cross-sectional analysis; it does not provide causal conclusions or intervention outcomes. The findings highlight associations between fatigue, mental health, and activity/sedentary behavior among predominantly remitted IBD patients.

If you experience fatigue, discussing activity patterns and mood with your care team may be helpful; this study suggests high-intensity exercise may be less tolerated by those with severe fatigue while walking and moderate activity were better tolerated in this sample.

Keep In Mind

This is a cross-sectional, hospital-based study from a single center; it shows associations, not cause-and-effect. Physical activity and sedentary time were self-reported via questionnaire. The sample had a high proportion of patients in clinical remission, which may affect generalizability.

Source Details

Review the original publication for the complete reporting, methods, and context.

Read Original Source
Research paper Evidence type derived from source or registry metadata.
PublicationFrontiers in Public Health
PublisherFrontiers Media SA
AuthorsMaría Dolores Herrera, Antoni Aguiló, Pedro Tauler +4 more
Study typeJournal Article
Indexed viaCrossref
Source typeResearch paper
PublishedAug 27, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

Related Reading

Browse latest news →