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Prevalence of Depressive Disorders in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta‐Analysis of Studies With Diagnoses Verified Using Structured Interviews
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Cure8 research brief

Prevalence of Depressive Disorders in Patients With Inflammatory Bowel Disease: A Systematic Review and Meta‐Analysis of Studies With Diagnoses Verified Using Structured Interviews

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Why This Matters

Depressive disorders—diagnosed using structured clinical interviews—appear to be relatively common in people with IBD, which has implications for screening and referral to mental health care within IBD clinics.

Who Should Pay Attention

Adults with IBD, gastroenterologists, mental health clinicians working with IBD patients, and researchers on psychiatric comorbidity in IBD.

Study Snapshot

Story typeResearch paper
Evidence typeResearch paper
Source depthJournal abstract

What To Know

This study pooled data from 12 independent studies (13 reports; 1,159 patients across 10 countries) that used structured or semi‑structured clinical interviews to diagnose depressive disorders in people with IBD.

The primary outcome was current MDD; secondary outcomes included current dysthymia, any current depressive disorder, and any lifetime depressive disorder. Current MDD prevalence was pooled at 13% (95% CI 4%–32%), dysthymia 4%, any current depressive disorder 18%, and any lifetime depressive disorder 30%.

The review did not find consistent differences in depressive disorder prevalence between Crohn's disease and ulcerative colitis. The authors caution that estimates are limited by the small number of studies and high between‑study heterogeneity.

Keep In Mind

Findings are drawn from a meta‑analysis of a small number of studies with substantial between‑study heterogeneity; prevalence estimates should be interpreted cautiously. This summary is grounded in the article abstract and not a review of full study reports.

Source Details

Review the original publication for the complete reporting, methods, and context.

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Research paper Evidence type derived from source or registry metadata.
PublicationJCC Plus
AuthorsLiling Xiao, Allan H. Young, Calum D. Moulton
InstitutionKing's College London
Study typeReview
Indexed viaOpenAlex
Source typeResearch paper
PublishedAug 10, 2026, 12:00 AM
Content availableJournal abstract

This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.

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