Cure8 research brief
This case highlights that full-thickness rectal prolapse in a toddler can be caused by very early-onset ulcerative colitis rather than isolated pediatric prolapse or allergy.
Early endoscopic evaluation and combining medical therapy (mesalazine) with a surgical measure to control prolapse were followed by clinical and biomarker improvement in this child.
parents and caregivers of young children with persistent rectal bleeding or prolapse; pediatric gastroenterologists, pediatric surgeons, and clinicians evaluating pediatric proctologic symptoms.
This report describes a 3-year-old boy whose very early-onset ulcerative colitis (VEO-UC) presented with full-thickness rectal prolapse and persistent mucoid hematochezia. He underwent diagnostic colonoscopy with biopsy, abdominal ultrasound, placement of a Thiersch anal cerclage (to reduce prolapse), and induction therapy with oral mesalazine.
Over six months the patient's Pediatric Ulcerative Colitis Activity Index (PUCAI) improved from 45 to 0, fecal calprotectin fell markedly, weight increased, hematochezia resolved by four weeks, and the prolapse did not recur.
The authors conclude that rectal prolapse can be an early sign of VEO-UC and that combined surgical and medical management led to anatomical stabilization and mucosal healing in this single case. This is a single observational case study reporting one child's diagnostic trajectory and outcome; it does not establish effectiveness beyond this patient.
Decisions about procedures or medications should remain individualized and discussed with a pediatric gastroenterologist.
This article is an observational single-patient case report (abstract-level summary). It describes one clinical course and outcome and does not prove general effectiveness or safety of the approach. Larger studies would be needed to generalize findings.
Review the original publication for the complete reporting, methods, and context.
This Cure8 brief is based on source text from the linked article. Cure8 is informational only and is not a substitute for professional medical advice, diagnosis, or treatment.
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