Condition

Inflammatory bowel disease

Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.

Page 9 of 87 · 4171 articles

Early-life animal exposure was not associated with risk of inflammatory bowel disease: a nationwide birth cohort study.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Early-life animal exposure was not associated with risk of inflammatory bowel disease: a nationwide birth cohort study.

This large, long-term study suggests that having pets or farm animals during pregnancy or early childhood probably does not meaningfully change a child’s later risk of developing IBD, which may reassure families...

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Statistical caution before adopting a data-driven day-3 PUCAI cut-off in flare-onset paediatric acute severe ulcerative colitis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Statistical caution before adopting a data-driven day-3 PUCAI cut-off in flare-onset paediatric acute severe ulcerative colitis.

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Digestive and liver...

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Prediction of incident inflammatory bowel disease from routine electronic health records: development and external validation of a longitudinal machine learning model

Earlier identification of people likely to develop IBD could shorten diagnostic delays that are linked to worse outcomes, and an automated EHR model might help target who should get earlier evaluation.

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Long-term comparative effectiveness of first-line infliximab vs corticosteroids in ulcerative colitis: Remission and colectomy risk
World Journal of Gastroenterology

Long-term comparative effectiveness of first-line infliximab vs corticosteroids in ulcerative colitis: Remission and colectomy risk

The study suggests that using infliximab as first-line therapy (rather than IV corticosteroids) may produce more durable remission and reduce long-term colectomy risk in moderate-to-severe ulcerative colitis.

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Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease
ClinicalTrials.gov

Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease

The trial is testing a personalized approach that uses CLE to find foods that directly disrupt the intestinal barrier and then removes those foods to see if patients feel and biologically improve. If successful, it could...

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Repurposing Fenofibrate in Modulating AMPK/NLRP3 Inflammasome in Patients With Ulcerative Colitis
ClinicalTrials.gov

Repurposing Fenofibrate in Modulating AMPK/NLRP3 Inflammasome in Patients With Ulcerative Colitis

A phase 2 trial tested whether repurposing fenofibrate (a lipid-lowering PPAR-α agonist) added to mesalamine can reduce disease activity and improve quality of life in adults with mild-to-moderate ulcerative colitis.

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An Open-Label Extension and Long-term Efficacy and Safety Monitoring Study of Patients With Crohn's Disease Previously Included in the Loss of RESponse to Ustekinumab Treated by Dose Escalation Study
ClinicalTrials.gov

An Open-Label Extension and Long-term Efficacy and Safety Monitoring Study of Patients With Crohn's Disease Previously Included in the Loss of RESponse to Ustekinumab Treated by Dose Escalation Study

This OLE study follows patients who lost response to ustekinumab every-8-week dosing and evaluates whether increasing to every-4-week dosing maintains efficacy and safety long-term. That question is directly relevant to...

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