Clinical study

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This model aims to identify healthy first‑degree relatives at higher risk of developing Crohn’s disease before symptoms start, which could enable earlier monitoring or preventive strategies. The score uses simple...

Some people with Crohn's disease still have symptoms even when inflammation is under control. This study suggests sulfur-producing gut bacteria and their metabolites might explain those lingering symptoms and point to...

The review brings together evidence that genetics, immune responses, the gut microbiome, and environmental triggers interact to cause Crohn's disease and ulcerative colitis.

Many people with Crohn’s disease continue to have symptoms even when inflammation is absent. This study suggests the gut microbiome — specifically sulfur-producing bacteria and hydrogen sulfide production — might explain...

Fatigue is common in people with Crohn’s disease and ulcerative colitis and can persist even when standard measures say the disease is in remission. This study suggests stricter definitions of remission don’t necessarily...

Perianal fistula complications are serious and difficult to treat. This study suggests starting anti-TNFα therapy early in pediatric Crohn disease may substantially lower the risk of developing these complications,...