Research topics
Genetics and genomics articles covering inherited risk, gene expression, disease pathways, and IBD research that connects genes to Crohn's disease, ulcerative colitis, or broader IBD.
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This paper highlights potential ubiquitination-related genes and immune-cell patterns that could help researchers understand Crohn’s disease biology and point to new targets for lab validation. For patients, it signals...
This study links a specific SERPINB4 gene mutation to impaired intestinal epithelial cell function in twins with Crohn’s disease, which could help explain how rare genetic variants contribute to disease in some patients.
Genetics can influence Crohn’s disease risk; knowing about risk genes and testing options may help people with a family history understand why disease runs in families and what testing can — and cannot — tell you. The...
The review brings together evidence that genetics, immune responses, the gut microbiome, and environmental triggers interact to cause Crohn's disease and ulcerative colitis.
