Article Archive

Page 11 of 99 · 4749 patient-friendly summaries

Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease
ClinicalTrials.gov

Impact of Diet and Lifestyle Modification on the Intestinal Barrier Integrity in Crohn's Disease

The trial is testing a personalized approach that uses CLE to find foods that directly disrupt the intestinal barrier and then removes those foods to see if patients feel and biologically improve. If successful, it could...

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Repurposing Fenofibrate in Modulating AMPK/NLRP3 Inflammasome in Patients With Ulcerative Colitis
ClinicalTrials.gov

Repurposing Fenofibrate in Modulating AMPK/NLRP3 Inflammasome in Patients With Ulcerative Colitis

A phase 2 trial tested whether repurposing fenofibrate (a lipid-lowering PPAR-α agonist) added to mesalamine can reduce disease activity and improve quality of life in adults with mild-to-moderate ulcerative colitis.

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An Open-Label Extension and Long-term Efficacy and Safety Monitoring Study of Patients With Crohn's Disease Previously Included in the Loss of RESponse to Ustekinumab Treated by Dose Escalation Study
ClinicalTrials.gov

An Open-Label Extension and Long-term Efficacy and Safety Monitoring Study of Patients With Crohn's Disease Previously Included in the Loss of RESponse to Ustekinumab Treated by Dose Escalation Study

This OLE study follows patients who lost response to ustekinumab every-8-week dosing and evaluates whether increasing to every-4-week dosing maintains efficacy and safety long-term. That question is directly relevant to...

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Clinical Study to Evaluate the Possible Efficacy of Nifuroxazide in Patient With Ulcerative Colitis
ClinicalTrials.gov

Clinical Study to Evaluate the Possible Efficacy of Nifuroxazide in Patient With Ulcerative Colitis

This trial tests whether adding the oral antibiotic nifuroxazide to standard mesalamine improves quality of life for people with mild-to-moderate ulcerative colitis. Results, if published, could suggest a new adjunctive...

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Don't leave home without it : Inflammatory Bowel Disease: Diagnosis and Treatment
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

Don't leave home without it : Inflammatory Bowel Disease: Diagnosis and Treatment

Based on the title and source metadata, this appears to be a patient education related to Inflammatory bowel disease and Tests and monitoring. The original article is from CMAJ : Canadian Medical Association journal =...

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If This Is A Test, Have I Passed Yet? Living with Inflammatory Bowel Disease
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

If This Is A Test, Have I Passed Yet? Living with Inflammatory Bowel Disease

Based on the title and source metadata, this appears to be a patient story related to Inflammatory bowel disease and Community and awareness. The original article is from CMAJ : Canadian Medical Association journal =...

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L-Proline Alleviates Dextran Sulfate Sodium-Induced Colitis by Remodeling Gut Microbiota and Inhibiting the NF-κB/STAT3 Signaling Pathway
MDPI AG

L-Proline Alleviates Dextran Sulfate Sodium-Induced Colitis by Remodeling Gut Microbiota and Inhibiting the NF-κB/STAT3 Signaling Pathway

The study suggests L‑proline can reduce colitis in a mouse model and reshapes the gut microbiome, raising the possibility that amino-acid–based dietary strategies might influence intestinal inflammation through...

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From Mitochondrial Targeting to Mechanistic Dependency in Nanoparticle Therapy for Ulcerative Colitis
Journal of Gastroenterology and Hepatology

From Mitochondrial Targeting to Mechanistic Dependency in Nanoparticle Therapy for Ulcerative Colitis

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of...

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Digital patient-reported outcomes to evaluate treatment response to filgotinib in patients with ulcerative colitis
Patient Related Outcome Measures

Digital patient-reported outcomes to evaluate treatment response to filgotinib in patients with ulcerative colitis

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Tests and monitoring. The original article is from Patient Related Outcome...

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Nanoformulated Curcumin Ameliorates Ulcerative Colitis via Gut Microbiota Modulation and Barrier Function Restoration
The American Journal of Chinese Medicine

Nanoformulated Curcumin Ameliorates Ulcerative Colitis via Gut Microbiota Modulation and Barrier Function Restoration

People with ulcerative colitis may be interested because the study explores a way to boost curcumin’s activity and suggests gut microbiota changes could underlie protection against colitis.

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B cells regulate T cell transfer colitis by partially reconstituting luminal IgA and modulating the colonic microbiota
Inflammatory Bowel Diseases

B cells regulate T cell transfer colitis by partially reconstituting luminal IgA and modulating the colonic microbiota

The study suggests B cells can protect against colitis through secretory IgA that reshapes the gut microbiota, a mechanism separate from known regulatory B cell cytokines. This could point to new directions for IBD...

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Inflammatory bowel disease and breast cancer: epidemiological evidence, shared biology, and clinical management.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]

Inflammatory bowel disease and breast cancer: epidemiological evidence, shared biology, and clinical management.

This review addresses whether people with IBD face higher breast cancer risk and how treatments for one disease might affect the other—questions many patients and clinicians raise when cancer and IBD overlap.

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Mechanisms of phosphorylation in colitis regulation: PP2Acα as an emerging therapeutic target for inflammatory bowel disease
Molecular Biology Reports

Mechanisms of phosphorylation in colitis regulation: PP2Acα as an emerging therapeutic target for inflammatory bowel disease

Based on the title and source metadata, this appears to be a basic science related to Inflammatory bowel disease, Drug Discovery, and Research and clinical trials. The original article is from Molecular Biology Reports.

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Real-World Epidemiology of Inflammatory Bowel Disease in Italy: Treatment Patterns, Adherence, and Costs in Patients with Ulcerative Colitis Treated with Mesalazine
Drugs - Real World Outcomes

Real-World Epidemiology of Inflammatory Bowel Disease in Italy: Treatment Patterns, Adherence, and Costs in Patients with Ulcerative Colitis Treated with Mesalazine

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Mesalamine. The original article is from Drugs - Real World Outcomes.

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