Evidence types

Systematic Review or Meta Analysis

Systematic review and meta-analysis articles covering combined evidence from multiple IBD studies. Research context emphasizes studies, trials, biomarkers, mechanisms, and emerging IBD science.

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Neglected kingdoms: the gut virome, mycobiome and their role in inflammatory bowel disease.
Gut microbes

Neglected kingdoms: the gut virome, mycobiome and their role in inflammatory bowel disease.

This review spotlights non-bacterial members of the gut microbiota (viruses and fungi) that may contribute to IBD by altering barrier function, immune responses, and interactions with bacteria. For people with IBD, these...

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Global research trends in ferroptosis in autoimmune diseases: a bibliometric and visual analysis (2018-2025).
Autoimmunity

Global research trends in ferroptosis in autoimmune diseases: a bibliometric and visual analysis (2018-2025).

The review shows increasing research linking ferroptosis to autoimmune diseases including IBD and ulcerative colitis, which may guide future biomarker and therapy research relevant to people with Crohn's disease or other...

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A scoping review on emerging biomarkers in inflammatory bowel disease: Towards precision medicine in diagnosis and therapeutic management.
PloS one

A scoping review on emerging biomarkers in inflammatory bowel disease: Towards precision medicine in diagnosis and therapeutic management.

New, non-invasive biomarkers and AI-driven multi-omic approaches could make diagnosis and treatment of IBD more precise, helping patients avoid invasive tests and improving chances of choosing effective therapies sooner.

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Crohn's Disease: From Immune Dysregulation to Intestinal Damage.
Inflammation

Crohn's Disease: From Immune Dysregulation to Intestinal Damage.

This review explains how genetic, microbial, immune, and stromal factors interact to cause Crohn’s disease, which helps explain why treatments often need to target specific immune pathways or biologic mechanisms....

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Meta-Analysis: Crohn's Disease Exclusion Diet for Induction and Maintenance in Crohn's Disease.

Dietary strategies such as the Crohn’s Disease Exclusion Diet (CDED) may help induce remission for some people with Crohn’s disease and could be an option alongside medical therapy or enteral nutrition. Patients...

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Immune cell-derived membrane nanovesicles: A promethean fire for autoimmune disease therapy through immune cell mimicry.

This review describes a novel, targeted drug-delivery approach being explored for autoimmune diseases including IBD; such technology could in future enable more specific immunomodulation with fewer systemic side effects...

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Epidemiology of primary sclerosing cholangitis in general and IBD populations: a systematic review and meta-analysis
Hepatology International

Epidemiology of primary sclerosing cholangitis in general and IBD populations: a systematic review and meta-analysis

PSC is rare in the general population but substantially more common in people with IBD, particularly ulcerative colitis, and it raises long-term hepatobiliary risks including cholangiocarcinoma—so knowing how often PSC...

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Artificial Intelligence Assisted Capsule endoscopy for Detection Lesions of Crohn's disease
frontiersin.org

Artificial Intelligence Assisted Capsule endoscopy for Detection Lesions of Crohn's disease

AI-assisted capsule endoscopy may improve detection of Crohn’s disease lesions and reduce missed findings, which could affect diagnosis and monitoring. People with IBD may see faster or more consistent reads of capsule...

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