Crohn's disease

Insurance changes and rising premiums can force people with Crohn’s disease to skip or lose access to expensive biologic medications and routine care, which patients in the article say led to loss of treatment options...

The article reviews current and emerging IBD treatments and the biological reasons they may work — useful for patients wanting to understand treatment options and future directions. It highlights therapies beyond...

Dietary components and processed vegetarian/vegan products may alter the gut microbiome and intestinal barrier — both are relevant to IBD. This study will directly compare common vegan products and meat substitutes with...

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Symptoms and flares. The original article is from msn.com.

Distinguishing IBD from gastrointestinal tuberculosis is challenging in regions where GITB is common; histologic markers like basal plasmacytosis and eosinophilia on mucosal biopsy could help guide diagnosis when...

Improving accuracy of IBD case identification in EMRs can make research and registries more reliable, reduce misclassification, and help ensure studies and quality programs use the right patient groups.

Cure8 could only read part of this source from hcplive.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Crohn's disease, Inflammatory bowel disease, and Community and awareness.

Based on the title and source metadata, this appears to be a market or business news related to Crohn's disease and Research and clinical trials. The original article is from firstwordpharma.com.

This article reports that Amgen is ending a Crohn’s disease target-discovery collaboration with TScan, which could slow or change an industry pathway for immune-targeted therapies discovered through that partnership....

Rising IBD prevalence across Asia means more people will need diagnosis, long-term care, and health-system resources; patterns differ by country and by Crohn's disease versus ulcerative colitis, which affects planning...

The study points to serum protein panels and tissue expression of glypican-6 (GPC6) as potential tools to diagnose or predict intestinal strictures in Crohn disease, which could help detect fibrosis earlier and guide...

A blood test that more reliably distinguishes UC from CD could reduce diagnostic uncertainty and help guide appropriate long‑term management for people with colonic inflammatory bowel disease.

The study will test whether routine point‑of‑care intestinal ultrasound changes clinical decisions compared with standard monitoring, which could make monitoring less invasive and more responsive if effective.

Researchers are testing whether targeting fungi with fluconazole can boost how well IL-23 biologics work for Crohn’s disease — if positive, this could point to a new adjunctive strategy to improve responses to biologic...

The trial could show whether a smart-label app plus clinician alerts improves medication adherence and downstream clinical outcomes for people with Crohn's disease or ulcerative colitis starting oral or subcutaneous...

An expanded access program can allow people with Crohn's disease or ulcerative colitis to access upadacitinib before local approval when no other suitable treatments exist.

People with IBD or Crohn's disease considering or taking upadacitinib may worry about rare but serious risks such as heart attacks, strokes, or blood clots. This meta-analysis found no clear increase in those events...

This real-world multicentre study evaluates risankizumab effectiveness and short-term persistence in adults with Crohn's disease, including those previously treated with ustekinumab — information that can help patients...

People with IBD on biologics or small molecules who live in or travel to areas where Coccidioides is endemic face a measurable risk of coccidioidomycosis. How the infection is classified (proven/probable/possible)...

ILD — a group of lung conditions — appears more common in people with ulcerative colitis than Crohn’s, and when present is linked with older age, more hospital use, and higher steroid use. That could affect monitoring...

The studies identify a metabolic reason why the inflamed gut struggles to heal: inflammation reduces an enzyme (QPRT) needed for NAD+ production, starving regenerating intestinal cells of energy. That suggests...

Cure8 could only read part of this source from tradingview.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Crohn's disease, and Research and clinical trials.

A dedicated Crohn’s and Colitis Center can coordinate advanced diagnostics, medical and surgical care, nutrition, and mental-health support — all of which can improve symptom management and quality of life. It also...

The study tests a new mechanism (TL1A inhibition) that may reduce inflammation and fibrosis in IBD. Positive phase 2b results suggest duvakitug could become another treatment option if later trials confirm benefit and...

If your colonoscopy found inflammation only in the terminal ileum, additional imaging with CTE identified more proximal small-bowel disease in about half of patients and often led to a diagnosis of Crohn’s disease.

Based on the title and source metadata, this appears to be a case report related to Crohn's disease and Complications. The original article is from Medical Mycology Case Reports.

This article summarizes positive phase IIb trial results for duvakitug (anti‑TL1A) in moderate‑to‑severe Crohn’s disease and ulcerative colitis, which could lead to a new targeted treatment option if later phase trials...

The review outlines new research tools for investigating whether mycobacteria contribute to Crohn’s disease and how the microbiome might influence infection and intestinal inflammation, which could eventually inform...

If validated, blood protein signatures that appear years before symptoms could help identify people at higher risk of Crohn’s disease and point to lifestyle or dietary measures that alter early biology.

Public figures talking about Crohn’s disease can raise awareness about how flares affect weight, appearance, hydration, and daily life, and may reduce stigma from uninformed comments.

Depression is common in people with IBD and can worsen quality of life and disease outcomes. This trial explores whether mirtazapine—an antidepressant thought to have favorable gastrointestinal tolerability—can be...

Standardized intestinal ultrasound scoring could help non-invasively monitor Crohn’s disease activity and reduce reliance on colonoscopy for some assessments. A high-sensitivity IUS score may be useful to rule out...

Auto-brewery syndrome can cause unexplained intoxication-like symptoms and may be under-recognized in people with Crohn’s disease. Recognizing gut fermentation as a possible cause can affect diagnostic testing and...

Smoking and similar nicotine-product use after Crohn's surgery appears linked to higher rates of endoscopic recurrence, which may affect postoperative monitoring and secondary-prevention strategies. Patients using HNBT...

This work suggests a new way Crohn’s disease might begin: a weaker early immune response (linked to NOD2 gene defects) allows small intestinal infections to persist and later trigger the inflammation that causes...

Postoperative endoscopic recurrence after ileocolic resection is an important risk for people with Crohn’s disease; this study links HNBT and possibly e-cigarette use to higher recurrence rates, which could affect...

This affects Crohn’s disease research funding and future drug-development pathways: a major pharmaceutical partner ended a collaboration that had aimed to discover T‑cell targets for Crohn’s disease, which could slow or...

This Taiwanese multicenter real-world study reports high 52-week clinical response and remission rates, sustained one-year drug persistence, and meaningful fistula healing with ustekinumab in patients with Crohn’s...

Accurate measurement of physical activity matters because it’s linked to symptoms, fitness, and overall health.

CAR-based cellular therapies could offer a new way to reset immune responses in some forms of IBD, potentially helping patients who do not respond to existing biologics or small molecules.

An FDA approval for an autoinjector of a biosimilar ustekinumab can make treatment easier to administer and may increase availability or affordability of a drug used to treat Crohn’s disease and ulcerative colitis....

Accurate, reliable measurement of ulcers and polyps during endoscopy can improve disease assessment and tracking for people with Crohn’s disease and ulcerative colitis and may better align visual findings with symptoms...

This trial tests whether the common sweetener sucralose alters the gut microbiome in people with Crohn’s disease in remission compared with healthy volunteers.

Diagnosis between UC, Crohn’s disease, and unclassified IBD can change in a meaningful minority of patients over years. Awareness of common reasons for reclassification (segmental disease, strictures) helps guide...

Dietary patterns like the Mediterranean diet may reduce inflammation and improve quality of life for people with Crohn’s disease by beneficially altering the gut microbiome and inflammatory markers. That could offer a...

An FDA approval of an autoinjector for ustekinumab may make self‑injection easier and more convenient for people with Crohn’s disease or ulcerative colitis who use this biologic. Changes in delivery format can also...

An obituary noting a life-long struggle with Crohn’s disease highlights the personal and community impact of IBD and links readers to a charity (Crohn’s and Colitis Canada) for donations.

New phase IIb trial results suggest an anti‑TL1A antibody (duvakitug) produced measurable benefit in both Crohn’s disease and ulcerative colitis, which could lead to a new treatment option if later phase III trials...