Condition

Inflammatory bowel disease

Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.

Page 11 of 87 · 4172 articles

Bimekizumab efficacy across GRAPPA domains to 3 years in patients with psoriatic arthritis: a post hoc analysis of two phase 3 studies.
Rheumatology (Oxford, England)

Bimekizumab efficacy across GRAPPA domains to 3 years in patients with psoriatic arthritis: a post hoc analysis of two phase 3 studies.

Patients with PsA and clinicians choosing long‑term biologic therapy may care about both durability of PsA control and safety signals for related inflammatory conditions like IBD and uveitis. This analysis reports...

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Challenges and opportunities facing inflammatory bowel disease in Sub-Saharan Africa: towards a contextually relevant research and practice agenda.
Journal of Crohn's & colitis

Challenges and opportunities facing inflammatory bowel disease in Sub-Saharan Africa: towards a contextually relevant research and practice agenda.

IBD cases are increasing in Sub-Saharan Africa but care and research remain limited and driven by high-income country priorities. Region-specific research and policy changes could improve diagnosis, treatment access, and...

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Type 6 secretion systems of adherent-invasive Escherichia coli isolated from Crohn's disease patients shape intestinal microbiota.
Europe PMC

Type 6 secretion systems of adherent-invasive Escherichia coli isolated from Crohn's disease patients shape intestinal microbiota.

The study identifies a bacterial mechanism (T6SS) that may help AIEC strains compete with normal gut microbes and colonize the intestinal mucosa — a process relevant to Crohn’s disease biology and future...

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Unraveling the Clinical Puzzle of Cerebral Venous Sinus Thrombosis in Ulcerative Colitis: Insights from a Systematic Review
Asian Journal of Neurosurgery

Unraveling the Clinical Puzzle of Cerebral Venous Sinus Thrombosis in Ulcerative Colitis: Insights from a Systematic Review

Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Ulcerative colitis, Inflammatory bowel disease, and Complications. The original article is from Asian Journal of...

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Therapeutic potential of maggot-derived bioactive peptides in modulating inflammatory responses in mice model of inflammatory bowel disease
Frontiers in cell and developmental biology

Therapeutic potential of maggot-derived bioactive peptides in modulating inflammatory responses in mice model of inflammatory bowel disease

Based on the title and source metadata, this appears to be a basic science related to Inflammatory bowel disease and Research and clinical trials. The original article is from Frontiers in cell and developmental biology.

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Association between Crohn’s disease and pulmonary nodule patterns: an inverse probability-weighted analysis of real-world data
Clinical and Translational Gastroenterology

Association between Crohn’s disease and pulmonary nodule patterns: an inverse probability-weighted analysis of real-world data

The study suggests pulmonary nodules are more common in people with Crohn’s disease and that age and certain medications (not disease phenotype) may better predict nodule burden — information that could influence how...

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Safety profile and potential favorable reporting signals of liraglutide in patients with ulcerative colitis: A FAERS pharmacovigilance and network pharmacology study
Pakistan Journal of Pharmaceutical Sciences

Safety profile and potential favorable reporting signals of liraglutide in patients with ulcerative colitis: A FAERS pharmacovigilance and network pharmacology study

This study raises pharmacovigilance signals and mechanistic hypotheses about liraglutide in people with ulcerative colitis — important because GLP-1 drugs are widely used and are being studied for inflammatory effects....

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OLFM4, LCN2 and FAM3B as Potential Biomarkers for Gut–Brain Axis Dysfunction in IBD-MDD Comorbidity
Genes

OLFM4, LCN2 and FAM3B as Potential Biomarkers for Gut–Brain Axis Dysfunction in IBD-MDD Comorbidity

People with IBD commonly experience mood disorders; identifying shared molecular signals could help explain why and point to biomarkers or targets for research. This study proposes three genes linked to conserved...

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Four dietary flavonoids differentially modulate the gut microbiota–barrier interaction against colitis-driven cognitive deficits
npj Science of Food

Four dietary flavonoids differentially modulate the gut microbiota–barrier interaction against colitis-driven cognitive deficits

Preclinical evidence suggests certain dietary flavonoids may protect the gut barrier, reshape the microbiome, and reduce neuroinflammation, which could be relevant to colitis-linked cognitive problems. This points to...

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Few-shot learning for expert consensus severity stratification in newly diagnosed crohn’s disease
Journal of Translational Medicine

Few-shot learning for expert consensus severity stratification in newly diagnosed crohn’s disease

Standardized, automated severity stratification at diagnosis could help guide early treatment planning and comparability across centers. An AI approach that approximates expert consensus may reduce variability in initial...

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PD-1 and PD-L1 Expression in Inflammatory Bowel Disease: A Paired Immunohistochemical Study
Biomedicines

PD-1 and PD-L1 Expression in Inflammatory Bowel Disease: A Paired Immunohistochemical Study

This study links higher mucosal PD-L1 expression to active IBD and routine disease activity measures, suggesting the PD-1/PD-L1 immune checkpoint may be involved in intestinal inflammation and could be a biomarker or...

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Tauroursodeoxycholic acid ameliorates DSS-induced ulcerative colitis via regulating TLR4/NLRP3/pyroptosis axis and Keap1/Nrf2 pathway and restoring gut barrier function.
European journal of pharmacology

Tauroursodeoxycholic acid ameliorates DSS-induced ulcerative colitis via regulating TLR4/NLRP3/pyroptosis axis and Keap1/Nrf2 pathway and restoring gut barrier function.

The study identifies a bile acid, TUDCA, that reduced colitis severity and improved gut-barrier and antioxidant pathways in mice, pointing to a potential new therapeutic approach for intestinal inflammation. This is...

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Distinct Microbiological Profile of Intra-Abdominal Abscesses in Crohn's Disease: A Multicenter Cohort Study from GETECCU.
Gastroenterologia y hepatologia

Distinct Microbiological Profile of Intra-Abdominal Abscesses in Crohn's Disease: A Multicenter Cohort Study from GETECCU.

Microbiological differences in Crohn’s-related abscesses could affect empirical antibiotic choices and highlight the importance of culture-directed therapy, especially in patients on immunosuppression who showed higher...

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The zc3h6 deficiency causes gut microbiota dysbiosis and inflammatory bowel disease-like symptoms in zebrafish.
Journal of genetics and genomics = Yi chuan xue bao

The zc3h6 deficiency causes gut microbiota dysbiosis and inflammatory bowel disease-like symptoms in zebrafish.

Based on the title and source metadata, this appears to be a basic science related to Inflammatory bowel disease, Microbiome, and Research and clinical trials. The original article is from Journal of genetics and...

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Adherence to advanced therapies in inflammatory bowel diseases: Real-world rates and predictors of non-adherence.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

Adherence to advanced therapies in inflammatory bowel diseases: Real-world rates and predictors of non-adherence.

Adherence affects how well advanced IBD treatments work. Knowing which drug forms and patient factors link to missed doses can help patients and clinicians plan support strategies.

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Prevalence of Enteric Hyperoxaluria in Crohn's Disease, Cystic Fibrosis, and After Bariatric Surgery: A Systematic Review
Europe PMC

Prevalence of Enteric Hyperoxaluria in Crohn's Disease, Cystic Fibrosis, and After Bariatric Surgery: A Systematic Review

Enteric hyperoxaluria increases risk of calcium oxalate kidney stones and kidney injury. Knowing how common EH is in Crohn's disease and after bariatric surgery helps identify who might benefit from screening and...

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Elective combined surgical management of concurrent gastrocolic and duodenocolic fistulae in longstanding Crohn's disease.
Clinical journal of gastroenterology

Elective combined surgical management of concurrent gastrocolic and duodenocolic fistulae in longstanding Crohn's disease.

Internal fistulae can be clinically silent yet serious in long-standing Crohn's disease. Early cross-sectional imaging detected rare gastrocolic and duodenocolic fistulae in this patient, and elective combined surgery...

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Deep Learning Based Automated Assessment of Ulcerative Colitis Endoscopic Severity Using Local Global Transformer and Graph Convolutional Networks
Springer Science and Business Media LLC

Deep Learning Based Automated Assessment of Ulcerative Colitis Endoscopic Severity Using Local Global Transformer and Graph Convolutional Networks

Automated, objective scoring of colonoscopy images could reduce variability in Mayo Endoscopic Score assignment and support treatment decisions and monitoring for people with ulcerative colitis.

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Role of AI in Accurate and Disinformation‐Resilient Diagnosis of Ulcerative Colitis
Disinformation Security for Generative AI Applications

Role of AI in Accurate and Disinformation‐Resilient Diagnosis of Ulcerative Colitis

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Disinformation Security...

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Mapping mitochondria-associated research in inflammatory bowel disease: A bibliometric and network analysis.
Medicine

Mapping mitochondria-associated research in inflammatory bowel disease: A bibliometric and network analysis.

This paper maps where and how mitochondria-related IBD research has grown and what themes (like mitophagy, metabolism, and machine learning) are emerging — useful for researchers, funders, and clinicians tracking...

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Contemporary multicentre validation and comparative performance of Day 1 prognostic scores in acute severe ulcerative colitis.
Journal of Crohn's & colitis

Contemporary multicentre validation and comparative performance of Day 1 prognostic scores in acute severe ulcerative colitis.

These Day 1 scores aim to identify patients unlikely to respond to IV steroids so treatment can be escalated earlier; that could shorten delays to rescue therapy and potentially improve outcomes for people admitted with...

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Plasma lipopolysaccharide-binding protein (LBP), a proxy for intestinal permeability, relates to clinicopathological and immunological disease activity in inflammatory bowel disease patients at diagnosis and during disease course.
Journal of Crohn's & colitis

Plasma lipopolysaccharide-binding protein (LBP), a proxy for intestinal permeability, relates to clinicopathological and immunological disease activity in inflammatory bowel disease patients at diagnosis and during disease course.

A simple blood marker (LBP) that reflects bacterial exposure across the gut barrier was linked to disease severity and immune activity at diagnosis and during follow-up—especially in ulcerative colitis—so it might help...

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Lactiplantibacillus plantarum HYY-DB36 alleviated dextran sulfate sodium (DSS)-induced ulcerative colitis through regulation of intestinal flora
Journal of Food Science and Technology

Lactiplantibacillus plantarum HYY-DB36 alleviated dextran sulfate sodium (DSS)-induced ulcerative colitis through regulation of intestinal flora

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of Food Science...

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Specialized macrophages link gut lymphoid follicles to Crohn’s disease granulomas
Springer Science and Business Media LLC

Specialized macrophages link gut lymphoid follicles to Crohn’s disease granulomas

The study helps explain how granulomas—linked to more severe Crohn’s disease—might form by repurposing lymphoid follicle macrophages, pointing to cellular programs and signals that could be relevant for future biomarkers...

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