Condition

Inflammatory bowel disease

Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.

Page 16 of 48 · 2295 articles

Induction-phase infliximab monitoring accelerates time to remission in pediatric IBD: a retrospective cohort study.
Crohn's & colitis 360

Induction-phase infliximab monitoring accelerates time to remission in pediatric IBD: a retrospective cohort study.

Faster remission can reduce symptoms, school disruption, and steroid exposure for children with IBD. If earlier infliximab level checks reliably speed remission, clinicians could adjust dosing sooner to improve outcomes.

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Pharmacological modulation of the PD-1/PD-L1 axis: from immune tolerance in colitis to immune escape in colorectal cancer.
European review for medical and pharmacological sciences

Pharmacological modulation of the PD-1/PD-L1 axis: from immune tolerance in colitis to immune escape in colorectal cancer.

The PD‑1/PD‑L1 pathway helps suppress harmful inflammation in IBD but can later allow colorectal tumors to avoid immune attack; understanding this balance matters for patients concerned about long‑term cancer risk and...

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Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs).
Cureus

Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs).

This meta-analysis pools randomized trial data and finds that FMT increased both clinical and endoscopic remission in ulcerative colitis versus placebo, which could matter to patients and clinicians exploring...

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Agricultural chemicals and gut microbiota dysbiosis: implications for the pathogenesis of inflammatory bowel disease.
Frontiers in nutrition

Agricultural chemicals and gut microbiota dysbiosis: implications for the pathogenesis of inflammatory bowel disease.

Environmental exposures from agricultural chemicals may affect the gut microbiome and intestinal inflammation, which could be one factor influencing IBD risk or flares. Understanding these links could point to preventive...

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Bioinspired Nanoparticles Deliver DNase I to Attenuate Ulcerative Colitis by Degrading NETs and Modulating PTGS2-Mediated ER Stress
Materials Today Bio

Bioinspired Nanoparticles Deliver DNase I to Attenuate Ulcerative Colitis by Degrading NETs and Modulating PTGS2-Mediated ER Stress

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Materials Today Bio.

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S1P receptor modulators for moderate-to-severe ulcerative colitis: a systematic review, meta-analysis, and trial sequential analysis
Journal of Gastroenterology

S1P receptor modulators for moderate-to-severe ulcerative colitis: a systematic review, meta-analysis, and trial sequential analysis

S1P receptor modulators are an emerging oral class of advanced therapy for moderate-to-severe ulcerative colitis; a systematic review that pools multiple RCTs helps clarify how effective and safe the class appears to be...

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Performance of the 2025 ASAS-Spartan Revised Classification Criteria for Axial Spondyloarthritis in a Canadian Multicenter Inception Cohort with Psoriasis, Uveitis, or Colitis Presenting with Undiagnosed Back Pain

The criteria were tested specifically in patients with psoriasis, uveitis, or IBD presenting with chronic back pain—groups at higher risk of axSpA—so results inform how well the new criteria perform in these real‑world...

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Vitamin D in mucosal healing: therapeutic potential and current evidence in inflammatory bowel disease
PubMed Central

Vitamin D in mucosal healing: therapeutic potential and current evidence in inflammatory bowel disease

Vitamin D may support intestinal barrier integrity and immune regulation—pathways central to mucosal healing and disease control in IBD. Understanding the evidence helps patients and clinicians consider vitamin D as a...

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Natural History of Concomitant Immune-Mediated Inflammatory Diseases: Psoriatic Disease and Inflammatory Bowel Disease Regarding Disease Course and Healthcare Utilization – A JANL-HIP Study

People with PsD or IBD — or both — may develop the other condition years later, and the order of diagnoses appears linked to timing of the second disease and to differences in mortality for some groups. That could affect...

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Comparative Analysis of Hospital Admissions and Costs for Psoriatic Disease, Inflammatory Bowel Disease, and Both Conditions in Newfoundland – A JANL-HIP Study

People with both IBD and another immune-mediated disease (psoriatic disease) had more hospital admissions and higher inpatient costs over ten years in this population.

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Screening Tools for Spondyloarthropathies Among Patients with Inflammatory Bowel Disease: A Scoping Review

SpA is a frequent but underrecognized extraintestinal manifestation in people with IBD; validated screening tools can help identify patients who need rheumatology evaluation. Earlier detection may address joint symptoms...

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To Clarify the Independent Role of Digital Learning and Nurse Support in the Self-Management of Inflammatory Bowel Disease
Digestive Diseases and Sciences

To Clarify the Independent Role of Digital Learning and Nurse Support in the Self-Management of Inflammatory Bowel Disease

Self-management support—whether through digital learning tools or nurse-delivered programs—can affect daily life for people with IBD. Understanding which element drives benefit could shape future care options and how...

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Mechanism and Active ingredients of Gancao Qinlian Granules in ameliorating ulcerative colitis:integrated in vivo, in vitro, network pharmacology and untargeted metabolomics investigation.
Journal of ethnopharmacology

Mechanism and Active ingredients of Gancao Qinlian Granules in ameliorating ulcerative colitis:integrated in vivo, in vitro, network pharmacology and untargeted metabolomics investigation.

The paper presents integrated preclinical evidence that a multi-herb formula (GQG) can reduce inflammation and alter gut microbiota and metabolites in a mouse model of ulcerative colitis, highlighting possible mechanisms...

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Efficacy and safety of ulcerative colitis therapies do not differ by age: A post hoc analysis of randomized controlled trials
PubMed Central

Efficacy and safety of ulcerative colitis therapies do not differ by age: A post hoc analysis of randomized controlled trials

Cure8 could only read part of this source from PubMed Central, so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and Research and clinical...

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Long-term outcomes of laser therapy for perianal fistulising Crohn’s disease: a single-center retrospective cohort study
Developments and Experiments in Health and Medicine

Long-term outcomes of laser therapy for perianal fistulising Crohn’s disease: a single-center retrospective cohort study

Perianal fistulas in Crohn’s disease are hard to treat and preserving continence is important. Long-term data suggesting laser ablation can achieve sustained healing in some patients are relevant for treatment decisions.

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Shifts in Mucosa‐Associated Microbiota Reflect Inflammation Gradient in Postoperative Crohn's Disease
JCC Plus

Shifts in Mucosa‐Associated Microbiota Reflect Inflammation Gradient in Postoperative Crohn's Disease

Microbial changes after ileocecal resection appear linked to the degree of postoperative inflammation; understanding these changes could help predict or prevent Crohn’s recurrence after surgery.

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Therapeutic Potential of Bioactive Natural Product in Crohn’s Disease: Focus on Redox Homeostasis and Inflammatory Signalling
Natural Products Analysis

Therapeutic Potential of Bioactive Natural Product in Crohn’s Disease: Focus on Redox Homeostasis and Inflammatory Signalling

People with Crohn’s may be interested because the review discusses novel natural compounds that target oxidative stress and inflammation — pathways involved in disease activity — and highlights formulation challenges...

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Proximally dominant inflammation at colonoscopy predicts pan-colonic histological remission following oral vancomycin therapy in pediatric ulcerative colitis
Digestive and Liver Disease

Proximally dominant inflammation at colonoscopy predicts pan-colonic histological remission following oral vancomycin therapy in pediatric ulcerative colitis

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Colonoscopy. The original article is from Digestive and Liver Disease.

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Prospective real-world experience with risankizumab in difficult-to-treat Crohn’s disease: results from the Dutch Initiative on Crohn and Colitis Registry
PubMed Central

Prospective real-world experience with risankizumab in difficult-to-treat Crohn’s disease: results from the Dutch Initiative on Crohn and Colitis Registry

The study provides real-world effectiveness and safety data for risankizumab in a largely difficult-to-treat Crohn's population, showing about half achieved corticosteroid-free clinical remission at 24 weeks —...

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Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study
PubMed Central

Inflammatory bowel disease and risk of perineal injury in primiparous vaginal births: a retrospective cohort study

This helps people with IBD and their care teams make delivery plans: if perianal disease is not active, having IBD alone was not linked to higher perineal injury risk in first-time vaginal births in this study.

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Modified Crohn's Disease Exclusion Diet and exclusive enteral nutrition (EEN) resolve oral dysbiosis in pediatric Crohn's disease: a prospective cohort study
PubMed Central

Modified Crohn's Disease Exclusion Diet and exclusive enteral nutrition (EEN) resolve oral dysbiosis in pediatric Crohn's disease: a prospective cohort study

The oral microbiome in children with Crohn's disease appears to reflect disease severity and changes with treatment, suggesting a potential noninvasive biomarker for monitoring response to nutritional therapies like CDED...

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Oral hydrogel systems in lower gastrointestinal disorders: From disease-based therapy to microbiota-guided design.
Materials today. Bio

Oral hydrogel systems in lower gastrointestinal disorders: From disease-based therapy to microbiota-guided design.

IBD and other lower-GI disorders may benefit from oral hydrogel platforms that improve local drug delivery while deliberately engaging the gut microbiota. Understanding this research direction helps patients and...

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Synergistic effects of partial enteral nutrition combined with Ustekinumab in induction and maintenance therapy for Crohn's disease: Real-world experience from a multicentre cohort.
Clinical nutrition (Edinburgh, Scotland)

Synergistic effects of partial enteral nutrition combined with Ustekinumab in induction and maintenance therapy for Crohn's disease: Real-world experience from a multicentre cohort.

Adding partial enteral nutrition to ustekinumab was associated with better clinical, endoscopic, radiologic, and nutritional outcomes at 52 weeks in this multicentre real-world cohort of Crohn’s disease patients. This...

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pH-responsive microgels containing multifunctional ginsenoside Rh2-based liposomes remodel intestinal environment to enhance celastrol therapy for ulcerative colitis.
Materials today. Bio

pH-responsive microgels containing multifunctional ginsenoside Rh2-based liposomes remodel intestinal environment to enhance celastrol therapy for ulcerative colitis.

The study describes a colon-targeted delivery system that enhanced local anti-inflammatory, barrier-repair, and microbiota-restoring effects of celastrol in a mouse UC model. If translatable, this approach could lead to...

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Discovery of self-assembled nanoparticles from Rubia cordifolia L. before and after carbonization and mechanistic study on their targeted therapy for ulcerative colitis
Phytomedicine

Discovery of self-assembled nanoparticles from Rubia cordifolia L. before and after carbonization and mechanistic study on their targeted therapy for ulcerative colitis

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Phytomedicine.

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Thymoquinone–chromium–psyllium nanocomposite mitigates ulcerative colitis in association with miR-200a/NRF2 enhancement and JAK/STAT modulation
Journal of Drug Delivery Science and Technology

Thymoquinone–chromium–psyllium nanocomposite mitigates ulcerative colitis in association with miR-200a/NRF2 enhancement and JAK/STAT modulation

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of Drug...

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Effects of Spirulina phycocyanin on Caco-2 cell injury and ulcerative colitis in mice
International Journal of Biological Macromolecules

Effects of Spirulina phycocyanin on Caco-2 cell injury and ulcerative colitis in mice

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from International Journal...

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Curcumin-loaded tetrahedral framework nucleic acids reshape intestinal homeostasis in ulcerative colitis by coordinating barrier repair, microbiota reconstruction, and immune modulation
Materials Today Bio

Curcumin-loaded tetrahedral framework nucleic acids reshape intestinal homeostasis in ulcerative colitis by coordinating barrier repair, microbiota reconstruction, and immune modulation

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Microbiome. The original article is from Materials Today Bio.

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A systematic review and meta-analysis of acupuncture for intestinal protection and underlying mechanisms in animal models of ulcerative colitis.
Medicine

A systematic review and meta-analysis of acupuncture for intestinal protection and underlying mechanisms in animal models of ulcerative colitis.

People with IBD may see growing interest in nonpharmacologic approaches like acupuncture; this review summarizes preclinical evidence suggesting acupuncture can reduce inflammation and support intestinal barrier proteins...

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Association between inflammatory bowel disease and ankylosing spondylitis: Mendelian randomization of a different database and meta-analysis.
Medicine

Association between inflammatory bowel disease and ankylosing spondylitis: Mendelian randomization of a different database and meta-analysis.

This study suggests that genetic risk for Crohn disease and ulcerative colitis may causally increase the risk of developing ankylosing spondylitis, an inflammatory joint condition that commonly co-occurs with IBD.

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The causal association between inflammatory bowel disease and pancreatitis: A 2-sample Mendelian randomization study.
Medicine

The causal association between inflammatory bowel disease and pancreatitis: A 2-sample Mendelian randomization study.

If true, a causal link between IBD and pancreatitis could help explain why people with Crohn’s disease or ulcerative colitis sometimes develop acute or chronic pancreatitis and could guide research into shared biological...

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Real-world data on clinical response to inflammatory bowel disease biological treatments in patients with concurrent primary sclerosing cholangitis: a case-control study.
Gastroenterology report

Real-world data on clinical response to inflammatory bowel disease biological treatments in patients with concurrent primary sclerosing cholangitis: a case-control study.

This study suggests that people with PSC-IBD may respond differently to some biologic treatments: infliximab and vedolizumab had similar early effectiveness versus IBD alone, but ustekinumab showed a lower early response...

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Clinical Characteristics of Patients Presenting with Moderate-to-Severe Atopic Dermatitis and Concomitant Inflammatory Bowel Diseases: a Multicenter Retrospective Study
Dermatology Practical & Conceptual

Clinical Characteristics of Patients Presenting with Moderate-to-Severe Atopic Dermatitis and Concomitant Inflammatory Bowel Diseases: a Multicenter Retrospective Study

This study suggests adults with moderate-to-severe atopic dermatitis may have a higher-than-expected prevalence of IBD compared with general population estimates, and AD often precedes IBD—so dermatologists and patients...

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