Condition

Inflammatory bowel disease

Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.

Page 17 of 88 · 4177 articles

Engineered E. coli Nissle 1917 alleviates colitis-associated depression via gut-brain axis restoration.
Science bulletin

Engineered E. coli Nissle 1917 alleviates colitis-associated depression via gut-brain axis restoration.

IBD patients often have depression and anxiety that current anti-TNF biologics do not adequately treat. An engineered probiotic that both neutralizes local TNFα and promotes GABA-producing microbes could address...

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Identification of CD40 as the target of artemisinin via targeted degradomics for ulcerative colitis.
Bioorganic chemistry

Identification of CD40 as the target of artemisinin via targeted degradomics for ulcerative colitis.

This study suggests an existing antimalarial drug, artemisinin, may reduce inflammation and improve gut barrier function in a mouse model of ulcerative colitis by targeting CD40 — a pathway relevant to immune-driven gut...

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Development and Evaluation of an Eudragit-Coated Colon-Targeted Delivery System for Myrica esculenta in Ulcerative Colitis.
Current pharmaceutical biotechnology

Development and Evaluation of an Eudragit-Coated Colon-Targeted Delivery System for Myrica esculenta in Ulcerative Colitis.

A colon-targeted delivery system could allow an anti-inflammatory plant extract (Myrica esculenta) to reach the colon with minimal systemic exposure, which may be relevant for developing localized treatments for...

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Rituximab-Induced Crohn's Disease-like Colitis Following Treatment for Post-transplant Lymphoproliferative Disorder in Chronic Active Epstein-Barr Virus Infection: A Case Report.
Internal medicine (Tokyo, Japan)

Rituximab-Induced Crohn's Disease-like Colitis Following Treatment for Post-transplant Lymphoproliferative Disorder in Chronic Active Epstein-Barr Virus Infection: A Case Report.

Atypical colitis occurring after rituximab is relevant to patients and clinicians because it may mimic Crohn's disease and require different management; recognizing drug‑associated colitis could affect diagnostic workup...

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Colonoscopic Intubation of the Appendix Through a Patulous Appendiceal Orifice in Ulcerative Colitis.
Internal medicine (Tokyo, Japan)

Colonoscopic Intubation of the Appendix Through a Patulous Appendiceal Orifice in Ulcerative Colitis.

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Procedures and surgery. The original article is from Internal medicine (Tokyo,...

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Commentary on "Case series of a novel inflammatory bowel disease phenotype (UC2CD) in Mexican patients".
Revista de gastroenterologia de Mexico (English)

Commentary on "Case series of a novel inflammatory bowel disease phenotype (UC2CD) in Mexican patients".

Based on the title and source metadata, this appears to be a case report related to Inflammatory bowel disease and Community and awareness. The original article is from Revista de gastroenterologia de Mexico (English).

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The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review.
Immunology

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review.

Researchers increasingly implicate innate lymphoid cells in IBD inflammation and mucosal barrier breakdown — findings that could guide future diagnostics or therapies. For patients, this helps explain research directions...

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Experiences and Factors Influencing the Transition to Adult Care in Adolescents With Inflammatory Bowel Disease: A Mixed-Methods Systematic Review.
Journal of clinical nursing

Experiences and Factors Influencing the Transition to Adult Care in Adolescents With Inflammatory Bowel Disease: A Mixed-Methods Systematic Review.

Transition to adult care is a high-risk time when adolescents with IBD can experience care gaps and worsened disease control. Understanding which fixed and modifiable factors affect transition can help patients,...

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A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting
ClinicalTrials.gov

A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting

This registry will collect real-world data on guselkumab use in adults with moderate-to-severe Crohn's disease or ulcerative colitis, focusing on how long patients stay on treatment, effectiveness in routine practice,...

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Investigating the Effect of the Non-nutritive Sweetener Sucralose in Inflammatory Bowel Disease
ClinicalTrials.gov

Investigating the Effect of the Non-nutritive Sweetener Sucralose in Inflammatory Bowel Disease

People with Crohn's disease often ask whether food additives and artificial sweeteners affect gut microbes or disease activity. This trial directly tests whether sucralose changes the fecal microbiome in adults with...

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Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
ClinicalTrials.gov

Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease

If gut microbes produce LPC/LPA that are linked to chronic abdominal pain, it could point to new biomarker or microbiome-targeted approaches for unexplained pain in IBD patients whose inflammation is quiet or minimal.

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Agomab Reports Positive Topline Data from STENOVA Open-Label Extension Study of Ontunisertib in Fibrostenosing Crohn's Disease

Patients with fibrostenosing Crohn’s disease have limited treatment options for the fibrotic strictures that can lead to procedures and surgery. These OLE findings suggest ontunisertib may be safe long-term and could...

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Timing of complementary food introduction is not associated with inflammatory bowel disease risk: A prospective birth cohort study
PubMed Central

Timing of complementary food introduction is not associated with inflammatory bowel disease risk: A prospective birth cohort study

Parents and clinicians often worry that when solids are started might change a child’s future risk of IBD. This large prospective study found no clear link between timing or patterns of complementary feeding and later...

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Between-visit care represents a substantial and underrecognized component of health care utilization in pediatric inflammatory bowel disease
PubMed Central

Between-visit care represents a substantial and underrecognized component of health care utilization in pediatric inflammatory bowel disease

If you or your child has pediatric-onset IBD, much of the care that supports disease management happens between scheduled visits. Recognizing this workload matters for access, clinician time, and policies that affect...

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Artificial Intelligence in Gastroenterology: Towards Explainable, Generalisable and Clinically Actionable Decision Support
Diagnostics

Artificial Intelligence in Gastroenterology: Towards Explainable, Generalisable and Clinically Actionable Decision Support

AI models are being developed to support IBD care (activity scoring, risk prediction), but most studies are retrospective and don’t yet demonstrate that AI outputs reliably change clinical decisions or improve outcomes....

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Inside Biotech: NeuroScientific appoints Southern Star Research to advance Phase 2 Crohn’s disease trial
au.finance.yahoo.com

Inside Biotech: NeuroScientific appoints Southern Star Research to advance Phase 2 Crohn’s disease trial

A new Phase 2 study of StemSmart™ could expand treatment options for patients with refractory or fistulising Crohn’s disease if later trials confirm safety and benefit. Appointment of a CRO is an early but important step...

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Multimethod screening identifies baicalein as a direct IDO1 inhibitor that restores tryptophan metabolism and repairs intestinal barrier in ulcerative colitis
Cell Biology and Toxicology

Multimethod screening identifies baicalein as a direct IDO1 inhibitor that restores tryptophan metabolism and repairs intestinal barrier in ulcerative colitis

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Cell Biology and...

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Upadacitinib Maintenance Therapy in Pediatric Ulcerative Colitis: 52-Week Multicenter Study From the Porto Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition
Clinical Gastroenterology and Hepatology

Upadacitinib Maintenance Therapy in Pediatric Ulcerative Colitis: 52-Week Multicenter Study From the Porto Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition

Based on the title and source metadata, this appears to be a clinical trial phase 3 related to Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. The original article is from Clinical Gastroenterology and...

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Selenium nanoparticles alleviate ulcerative colitis by regulating macrophage mitochondrial dynamics
Free Radical Biology and Medicine

Selenium nanoparticles alleviate ulcerative colitis by regulating macrophage mitochondrial dynamics

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Free Radical Biology...

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Autophagy modulation in ulcerative colitis with traditional Chinese medicine: A review
Pathology - Research and Practice

Autophagy modulation in ulcerative colitis with traditional Chinese medicine: A review

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Pathology - Research...

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Colon-targeted mucin/cyclosporine A co-loaded microspheres synergistically ameliorate ulcerative colitis via immunosuppression and mucosal barrier repair
Colloids and Surfaces B: Biointerfaces

Colon-targeted mucin/cyclosporine A co-loaded microspheres synergistically ameliorate ulcerative colitis via immunosuppression and mucosal barrier repair

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Colloids and Surfaces...

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