Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 58 of 88 · 4195 articles
An AI-derived score that combines inflammation severity and extent may better predict relapse risk in ulcerative colitis than severity alone. That could help identify patients in endoscopic remission who still face...
The study suggests why a JAK1 inhibitor (filgotinib) may work better in some gut regions than others, offering a possible explanation for mixed clinical trial results in Crohn's disease. This could influence how future...
This study identifies a plant-derived compound (poricoic acid A) that reduced inflammation, cellular senescence, and colon injury in cell and mouse models of ulcerative colitis and links those effects to AMPK/PPARγ...
If approved, a vedolizumab biosimilar could increase access to an established IBD biologic by offering a lower-cost alternative, potentially reducing barriers to starting or continuing treatment for people with...
Intestinal fibrosis is a serious complication of long-standing ulcerative colitis. Identifying NET-related biomarkers (IL1RN, MUC1, SERPINA1) could help researchers develop better diagnostic tools or treatments targeting...
The study nominates specific compounds and molecular targets from a traditional herbal formulation that could be investigated as potential anti-inflammatory agents for ulcerative colitis, helping bridge chemical...
An updated FDA drug label affects how ustekinumab is prescribed and monitored. It confirms Crohn’s disease and ulcerative colitis as approved uses and highlights safety concerns (infections, TB screening, malignancy)...
HLH is a rare but life‑threatening complication that can be triggered by herpesvirus infection in immunosuppressed IBD patients. Awareness may speed diagnosis and treatment for symptomatic patients on therapies like JAK...
Older adults with IBD are at higher risk of functional decline; SE and PT are low-risk interventions that may help reduce frailty, sarcopenia, fatigue, joint pain, and improve postoperative recovery and quality of life.
People with IBD and those on commonly used biologics may have different early T cell responses and faster waning after SARS-CoV-2 vaccination, which could affect timing or interpretation of immune monitoring and booster...
Disability related to IBD affects daily functioning and quality of life; identifying factors linked with higher or lower disability (vitamin D status, azathioprine use, smoking) can help patients and clinicians consider...
Cure8 could only read part of this source from Crohn's & colitis 360, so this card uses cautious topic tags instead of a full summary. It is tagged for Inflammatory bowel disease and Procedures and surgery.
Fatigue is a common, impactful symptom in pediatric and young-adult IBD but is poorly defined and measured, limiting the ability to design age-appropriate supports. This review highlights gaps that affect patients' daily...
CDI occurs more often in hospitalized people with IBD than in those without IBD. Understanding which patients are at higher risk for death or complications can help hospitals prioritize early testing and management to...
Extraintestinal manifestations (EIMs) can significantly affect people with IBD and may require multidisciplinary care. Knowing how often EIMs are documented and which patients are more likely to have them helps...
The paper reports a material that preserved barrier proteins and reduced inflammatory signaling in cell and mouse models of ulcerative colitis; this could point to a low-cost adjunct approach for protecting the colonic...
PROM completion is important for monitoring symptoms and disease control between visits. The study shows a single empowerment campaign produced a short‑term boost in PROM response but not sustained engagement,...
Researchers found distinct microbial and host molecular features in the appendices of children with IBD, which could help explain local immune activation and guide future studies of disease mechanisms or biomarkers.
Crohn's can affect more than the gut; a coordinated multidisciplinary team helps manage intestinal disease plus common extraintestinal issues (nutrition, skin, joints, eyes, mental health). Knowing which specialists to...
This research links a bacterial surface capsule to how well a gut microbe colonizes the intestine and to lower inflammatory responses in mouse models, which may help explain strain differences seen in Crohn’s disease and...
A market analysis listing late‑stage investigational therapies and growing use of IL‑23 and S1P pathway drugs signals potential new treatment options and changing prescribing patterns that may affect access, choice, and...
Cure8 found this source from medpagetoday.com, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease, Crohn's disease, and Irritable bowel syndrome. Open the original article for the...
The work links fungal strain variation to differences in adhesion and immune recognition, which could help explain why a normally food-associated yeast is found in Crohn disease ulcers and point to microbial features...
If validated, transient modulation of epithelial E‑cadherin could become a new approach to promote mucosal healing — a key goal in IBD care. The findings point to epithelial repair biology rather than an approved patient...
The report shows a guideline-grounded AI tool for IBD professionals can be deployed internationally and attract repeated use, suggesting potential for AI to help synthesize guideline information.
The study tests whether adding MRI-based transmural assessment to a fecal-calprotectin–guided (CALM) strategy improves the ability to keep people with Crohn’s disease in corticosteroid-free clinical remission and may...
The trial tests ustekinumab dosing, safety, and pharmacokinetics specifically in children with moderate–severe Crohn’s — information that can affect pediatric treatment options and dosing guidance once results are...
Dietary strategies are commonly considered by people with IBD to manage symptoms and quality of life. This trial focuses on real-world adherence and patient-reported barriers to three popular diets (intermittent fasting,...
If sodium intake influences gut proteolytic activity, microbiota and inflammation, the findings could help tailor dietary guidance and personalized nutrition strategies for people with Crohn’s disease.
MR enterography is an important tool to measure transmural inflammation in ileal Crohn's disease, but many patients find the oral distension agents unpleasant. Demonstrating that non-distended MR enterography yields...
New analytical tools for longitudinal microbiome data can reveal time-varying microbial signatures tied to Crohn's disease and ulcerative colitis. Identifying such biomarkers may eventually inform diagnosis, monitoring,...
Low zinc levels were linked with higher one-year relapse risk in UC patients in remission; knowing zinc status might add prognostic information beyond standard labs.
Older adults with ulcerative colitis can rarely develop large-vessel giant cell arteritis as an extraintestinal complication.
Lung involvement is an underrecognized extraintestinal complication in IBD and can reflect disease activity, altered gut–lung immune signaling, or medication toxicity — distinguishing the cause is important for...
CDI is a common and important complication in people with IBD; which antibiotic is used can affect recurrence risk and subsequent need for surgery. This review pools available studies and suggests vancomycin may reduce...
HLH is a rare but serious complication in immunosuppressed IBD patients; visceral leishmaniasis can trigger HLH and may be overlooked outside endemic areas. Early bone marrow assessment can speed diagnosis and treatment.
Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Imaging. The original article is from Scandinavian Journal of Gastroenterology.
The study identifies a compound (DDIE) that reduced cellular senescence and improved colitis in a mouse model by modulating AKT and GSK3B, suggesting a new avenue for drug development in ulcerative colitis focused on...
The study describes a novel hydrogel designed to deliver sinapic acid directly to the inflamed colon and release drug in response to a reducing environment—an approach that could improve targeted oral therapies for...
The study links paternal exposure to an emerging PFAS chemical (OBS) with epigenetic changes in sperm that may increase offspring susceptibility to colitis, highlighting a possible environmental pathway relevant to IBD...
Cure8 found this source from Nature genetics, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Research and clinical trials. Open the original article for the full details.
Personalizing adalimumab dosing could reduce underexposure, treatment failure, and immunogenicity for people with IBD. Validated popPK models are a key step toward reliable model-informed precision dosing in clinical...
The study identifies a plant extract that reduced inflammation and oxidative stress and altered molecular pathways (Nrf2/Keap1, NF-κB) and lncRNA expression in a rat colitis model—potential leads for future IBD research...
The work suggests a microbe–metabolite–immune pathway (B. pseudolongum → taurine metabolites → M2 macrophages) that could point to future microbiome- or metabolite-targeted therapies for ulcerative colitis, which may be...
IBD may involve small-vessel changes beyond the gut. If reproducible, retinal microvascular alterations detectable by OCTA could offer a non-invasive window into systemic microvascular involvement in IBD.
Fatigue is a frequent, impactful symptom in IBD. Identifying that reduced physical fitness (rather than just lower day-to-day activity) is linked to fatigue points toward targeted fitness training as a potential way to...
The study links symptom trajectories during the first year of biologic treatment to endoscopic remission, suggesting that week 20 symptom assessment may help predict long-term outcomes for people with UC on biologics.
The study suggests a herbal formula (H7F) may protect intestinal barrier function, modulate the gut microbiome, and suppress IL-17/NF-κB inflammation in a mouse colitis model—mechanisms relevant to IBD pathophysiology.
