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Ulcerative colitis

Ulcerative colitis news across medications, symptoms, monitoring, procedures, research, access, and daily life.

Page 8 of 40 · 1914 articles

Integrated Metagenomic and Host Transcriptomic Profiling Reveals Microbial Enzyme-Driven Immunometabolic Remodeling in Ulcerative Colitis: A Multi-Omics Bioinformatics Analysis
Enzyme and Microbial Technology

Integrated Metagenomic and Host Transcriptomic Profiling Reveals Microbial Enzyme-Driven Immunometabolic Remodeling in Ulcerative Colitis: A Multi-Omics Bioinformatics Analysis

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Enzyme and Microbial...

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Clinical and Psychosocial Burden of Inflammatory Bowel Disease Among Transgender Individuals: A National BioResource Cohort Study

This study suggests transgender and gender non-conforming people with IBD may face longer diagnostic delays, higher psychiatric comorbidity, and possibly more hospitalisations or surgery. That could mean gaps in care or...

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Best-practice recommendations for the transition care pathway for children and young people with moderate to severe ulcerative colitis: a modified Delphi panel with UK health care professionals
Frontline Gastroenterology

Best-practice recommendations for the transition care pathway for children and young people with moderate to severe ulcerative colitis: a modified Delphi panel with UK health care professionals

Transition from paediatric to adult services is a high-risk period for gaps in care. Consensus recommendations aim to standardise pathways, support young people’s needs, and reduce barriers to effective treatment.

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Limosilactobacillus reuteri Z-621 isolated from Hu lambs alleviates colitis by restoring intestinal barrier homeostasis and modulating the gut microbiota composition and lipid metabolism
Animal Microbiome

Limosilactobacillus reuteri Z-621 isolated from Hu lambs alleviates colitis by restoring intestinal barrier homeostasis and modulating the gut microbiota composition and lipid metabolism

The paper identifies a specific probiotic strain that reduced colitis signs and improved intestinal barrier function in a mouse model, supporting further preclinical and translational work toward microbiome-based...

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Systematic Review: Inclusion of Patients With Difficult-to-Treat Inflammatory Bowel Disease in Randomized Controlled Trials of Advanced Therapies.
Alimentary pharmacology & therapeutics

Systematic Review: Inclusion of Patients With Difficult-to-Treat Inflammatory Bowel Disease in Randomized Controlled Trials of Advanced Therapies.

People with IBD who have failed multiple advanced therapies are often the most difficult to treat, yet this review shows they are under-represented in clinical trials. That limits direct evidence about how well new...

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Integrated transcriptome and single-cell RNA sequencing identifies transient receptor potential channel-related biomarkers in ulcerative colitis
Frontiers in Molecular Biosciences

Integrated transcriptome and single-cell RNA sequencing identifies transient receptor potential channel-related biomarkers in ulcerative colitis

New biomarkers and cell-type insights could help future diagnostic tools or targeted therapies in UC by pointing to TRP channel–related genes and B/plasma cell involvement.

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Genome-wide analysis of genetic modifiers of Crohn's disease and ulcerative colitis risk in response to tobacco smoking.
EBioMedicine

Genome-wide analysis of genetic modifiers of Crohn's disease and ulcerative colitis risk in response to tobacco smoking.

The work helps explain why smoking increases Crohn’s risk but seems protective for ulcerative colitis by identifying genetic loci and smoking-dependent gene expression changes that differ between the two diseases. That...

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Identification of CD40 as the target of artemisinin via targeted degradomics for ulcerative colitis.
Bioorganic chemistry

Identification of CD40 as the target of artemisinin via targeted degradomics for ulcerative colitis.

This study suggests an existing antimalarial drug, artemisinin, may reduce inflammation and improve gut barrier function in a mouse model of ulcerative colitis by targeting CD40 — a pathway relevant to immune-driven gut...

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Development and Evaluation of an Eudragit-Coated Colon-Targeted Delivery System for Myrica esculenta in Ulcerative Colitis.
Current pharmaceutical biotechnology

Development and Evaluation of an Eudragit-Coated Colon-Targeted Delivery System for Myrica esculenta in Ulcerative Colitis.

A colon-targeted delivery system could allow an anti-inflammatory plant extract (Myrica esculenta) to reach the colon with minimal systemic exposure, which may be relevant for developing localized treatments for...

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Colonoscopic Intubation of the Appendix Through a Patulous Appendiceal Orifice in Ulcerative Colitis.
Internal medicine (Tokyo, Japan)

Colonoscopic Intubation of the Appendix Through a Patulous Appendiceal Orifice in Ulcerative Colitis.

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Procedures and surgery. The original article is from Internal medicine (Tokyo,...

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A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting
ClinicalTrials.gov

A Study to Assess Guselkumab in Participants With Moderate-to-Severe Inflammatory Bowel Disease in Real Life Italian Setting

This registry will collect real-world data on guselkumab use in adults with moderate-to-severe Crohn's disease or ulcerative colitis, focusing on how long patients stay on treatment, effectiveness in routine practice,...

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Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease
ClinicalTrials.gov

Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease

If gut microbes produce LPC/LPA that are linked to chronic abdominal pain, it could point to new biomarker or microbiome-targeted approaches for unexplained pain in IBD patients whose inflammation is quiet or minimal.

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Timing of complementary food introduction is not associated with inflammatory bowel disease risk: A prospective birth cohort study
PubMed Central

Timing of complementary food introduction is not associated with inflammatory bowel disease risk: A prospective birth cohort study

Parents and clinicians often worry that when solids are started might change a child’s future risk of IBD. This large prospective study found no clear link between timing or patterns of complementary feeding and later...

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Multimethod screening identifies baicalein as a direct IDO1 inhibitor that restores tryptophan metabolism and repairs intestinal barrier in ulcerative colitis
Cell Biology and Toxicology

Multimethod screening identifies baicalein as a direct IDO1 inhibitor that restores tryptophan metabolism and repairs intestinal barrier in ulcerative colitis

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Cell Biology and...

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Upadacitinib Maintenance Therapy in Pediatric Ulcerative Colitis: 52-Week Multicenter Study From the Porto Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition
Clinical Gastroenterology and Hepatology

Upadacitinib Maintenance Therapy in Pediatric Ulcerative Colitis: 52-Week Multicenter Study From the Porto Group of the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition

Based on the title and source metadata, this appears to be a clinical trial phase 3 related to Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. The original article is from Clinical Gastroenterology and...

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Selenium nanoparticles alleviate ulcerative colitis by regulating macrophage mitochondrial dynamics
Free Radical Biology and Medicine

Selenium nanoparticles alleviate ulcerative colitis by regulating macrophage mitochondrial dynamics

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Free Radical Biology...

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Autophagy modulation in ulcerative colitis with traditional Chinese medicine: A review
Pathology - Research and Practice

Autophagy modulation in ulcerative colitis with traditional Chinese medicine: A review

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Pathology - Research...

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Colon-targeted mucin/cyclosporine A co-loaded microspheres synergistically ameliorate ulcerative colitis via immunosuppression and mucosal barrier repair
Colloids and Surfaces B: Biointerfaces

Colon-targeted mucin/cyclosporine A co-loaded microspheres synergistically ameliorate ulcerative colitis via immunosuppression and mucosal barrier repair

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Colloids and Surfaces...

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Cinnamaldehyde-hollow mesoporous Prussian blue nanozymes for ulcerative colitis via reactive oxygen and nitrogen species scavenging and gut microbiota-metabolism modulation
Journal of Drug Delivery Science and Technology

Cinnamaldehyde-hollow mesoporous Prussian blue nanozymes for ulcerative colitis via reactive oxygen and nitrogen species scavenging and gut microbiota-metabolism modulation

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Microbiome. The original article is from Journal of Drug Delivery Science and...

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Synergistic polyphenol nanozyme–DNAzyme targeting of M1 macrophages for STAT1 silencing and inflammation suppression in ulcerative colitis
Chemical Engineering Journal

Synergistic polyphenol nanozyme–DNAzyme targeting of M1 macrophages for STAT1 silencing and inflammation suppression in ulcerative colitis

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Chemical Engineering...

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Nanogel-coated nanozymes for ulcerative colitis targeted treatment by restoring redox homeostasis and anti-inflammatory activity
Colloids and Surfaces B: Biointerfaces

Nanogel-coated nanozymes for ulcerative colitis targeted treatment by restoring redox homeostasis and anti-inflammatory activity

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Colloids and Surfaces...

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Pharmacological investigation of a selected triazole derivative against acetic acid-induced ulcerative colitis in mouse model
Biochemical and Biophysical Research Communications

Pharmacological investigation of a selected triazole derivative against acetic acid-induced ulcerative colitis in mouse model

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis and Research and clinical trials. The original article is from Biochemical and Biophysical Research Communications.

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Inhibition of CDK9 improves colonic epithelial dysfunction in DSS-induced ulcerative colitis mice by blocking the IL-6/STAT3 signaling pathway.
Molecular immunology

Inhibition of CDK9 improves colonic epithelial dysfunction in DSS-induced ulcerative colitis mice by blocking the IL-6/STAT3 signaling pathway.

The study identifies CDK9 inhibition as a way to reduce IL‑6/STAT3 signaling and protect the colonic epithelial barrier in preclinical models, suggesting a potential new therapeutic approach for ulcerative colitis...

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Mechanistic interactions between inflammatory bowel disease and obstructive sleep apnea.
Sleep medicine reviews

Mechanistic interactions between inflammatory bowel disease and obstructive sleep apnea.

IBD and obstructive sleep apnea may influence each other through shared biological processes (barrier dysfunction, dysbiosis, immune activation, intermittent hypoxia), so understanding this could affect screening and...

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Viral–Gut Microbiota Interactions: Implications for the Gut Mucosa in Inflammatory Bowel Disease
International Journal of Molecular Sciences

Viral–Gut Microbiota Interactions: Implications for the Gut Mucosa in Inflammatory Bowel Disease

Viruses in the gut (including bacteriophages) could influence inflammation and the intestinal barrier in IBD, so understanding the virome may point to new research directions or therapies.

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Gut Microbiota, Inflammatory Bowel Disease and the Prioritization of Host Effector Genes: A Two-Sample Mendelian Randomization Study with Independent Replication, cis-eQTL Colocalization and Single-Cell Localization
International Journal of Molecular Sciences

Gut Microbiota, Inflammatory Bowel Disease and the Prioritization of Host Effector Genes: A Two-Sample Mendelian Randomization Study with Independent Replication, cis-eQTL Colocalization and Single-Cell Localization

The work suggests specific host genes and cell types that might mediate links between gut microbes and IBD, which could direct future laboratory research into mechanisms and potential biomarkers.

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Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Mymensingh medical journal : MMJ

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.

Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...

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Anti-inflammatory activity of Chlorella polysaccharide AHP.
Molecular and cellular biochemistry

Anti-inflammatory activity of Chlorella polysaccharide AHP.

The study reports that Chlorella-derived polysaccharide AHP reduced inflammation, supported barrier repair, and changed gut microbiota in cell and mouse colitis models—suggesting a potential new bioactive candidate for...

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Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea
Journal of Pharmacoepidemiology and Risk Management

Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea

This paper suggests children and teens with ulcerative colitis have higher rates of diagnosed mental disorders and antidepressant use compared with peers, indicating mental-health needs are an important part of pediatric...

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Synbiotics administration leads to attenuated mucosal inflammatory neutrophil infiltration and increased hematocrit in experimental ulcerative colitis
Cirugía y Cirujanos (English Edition)

Synbiotics administration leads to attenuated mucosal inflammatory neutrophil infiltration and increased hematocrit in experimental ulcerative colitis

Cure8 could only read part of this source from Cirugía y Cirujanos (English Edition), so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and...

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Advanced endoscopy and artificial intelligence-enabled vascular healing for ulcerative colitis: promising frontiers or mere mirage?
Clinical Endoscopy

Advanced endoscopy and artificial intelligence-enabled vascular healing for ulcerative colitis: promising frontiers or mere mirage?

If validated, AI-enhanced vascular assessment during endoscopy could give clearer, more reproducible information about mucosal and histologic healing — which matters for monitoring disease activity and guiding treatment...

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Upadacitinib Is Associated with the Lowest Risk of Treatment Failure Among Advanced Therapies for Ulcerative Colitis: A Real-World Administrative Claims Study.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Upadacitinib Is Associated with the Lowest Risk of Treatment Failure Among Advanced Therapies for Ulcerative Colitis: A Real-World Administrative Claims Study.

This large real-world study found upadacitinib was associated with lower risk of treatment failure and more corticosteroid-free stability compared with several other advanced therapies for ulcerative colitis —...

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Low Phase angle is a marker of deteriorated nutritional status and indicates a more active and endoscopically severe inflammatory bowel disease.
Clinical nutrition ESPEN

Low Phase angle is a marker of deteriorated nutritional status and indicates a more active and endoscopically severe inflammatory bowel disease.

Phase angle, an easy-to-measure BIA parameter, was lower in IBD patients with malnutrition and higher disease activity. Detecting malnutrition earlier could matter for patients' strength, healing, and overall outcomes.

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