Page 20 of 100 · 4760 patient-friendly summaries
Based on the title and source metadata, this appears to be an observational study related to Inflammatory bowel disease and Mental health and quality of life. The original article is from medscape.com.
A new Phase 2 study of StemSmart™ could expand treatment options for patients with refractory or fistulising Crohn’s disease if later trials confirm safety and benefit. Appointment of a CRO is an early but important step...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Cell Biology and...
Simpler patient-reported scores (PRO2/PRO3) were much more often available in routine clinic visits than CDAI or HBI, yet they agreed closely with those indices. That could make regular monitoring and telehealth...
Cure8 found this source from tipranks.com, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. Open the original article for the...
Based on the title and source metadata, this appears to be a clinical trial phase 3 related to Ulcerative colitis, Inflammatory bowel disease, and Upadacitinib. The original article is from Clinical Gastroenterology and...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Free Radical Biology...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Pathology - Research...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Colloids and Surfaces...
A single‑patient report suggests guselkumab (IL‑23 inhibitor) may control both refractory pyoderma gangrenosum and coexisting Crohn disease when several prior treatments failed.
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Microbiome. The original article is from Journal of Drug Delivery Science and...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Chemical Engineering...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Colloids and Surfaces...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis and Research and clinical trials. The original article is from Biochemical and Biophysical Research Communications.
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease and Diet and lifestyle. The original article is from European Journal of Integrative Medicine.
Many reproductive-aged women with IBD and other autoimmune conditions may not have documented claims for prescription or permanent contraception, including women taking medications with potential fetal risks. That gap...
A multimodal, simpler activity score could improve practical disease monitoring when full ileocolonoscopy isn’t possible and help standardize treat-to-target practice across centers.
The study identifies an A. muciniphila strain (WW001) that strengthened barrier function and reduced inflammation in lab and mouse models of colitis, pointing to a possible microbiome-based probiotic strategy for IBD...
Many people with Crohn’s are given dietary limits (here, ~30 g fat/day) after flares or hospitalization. Practical, sustainable food-choice strategies can help patients follow such advice and reduce meal-related stress.
FMT is an active area of research that could affect future IBD treatments; patients with IBD commonly experience obesity and complex care decisions. Updates on FDA-approved FMT products and ongoing Crohn’s studies may...
The review and original research highlighted here focus on AI-driven multi-omics and single-cell approaches that aim to improve biomarker discovery, diagnosis, and personalized treatment strategies relevant to Crohn’s...
Routinely collected healthcare data can reveal how Crohn’s disease is managed and experienced in everyday practice, helping fill gaps left by clinical trials. A broader, data-driven measure of disease burden could better...
Interstitial lung disease (ILD) is an underrecognized extraintestinal complication in IBD that in this study was relatively common (12%) and associated with a substantially increased risk of death.
Mothers with chronic diseases such as MS and IBD appear to have higher rates of peripartum mental illness requiring care across serial pregnancies, so awareness and monitoring during and between pregnancies may be...
A validated prediction score that reliably rules out clinically significant CT findings could reduce unnecessary CT imaging, radiation exposure, and costs for people with Crohn's disease experiencing acute symptoms.
Circulating glycoprotein signals may help explain how systemic inflammation in IBD interacts with metabolic liver disease (MASLD). If validated, they could improve risk stratification for liver complications beyond...
Organoid models aim to reproduce human intestinal biology more closely than traditional cell lines or animal models, which could improve understanding of IBD mechanisms and help develop or personalize therapies.
This press release signals a step toward a new local, regenerative approach for treating complex perianal fistulas—a difficult Crohn’s complication with limited options. If clinical trials proceed, the therapy could add...
The study shows functional differences in how Crohn’s versus healthy fecal microbiota ferment substrates, with CD cultures making less beneficial butyrate and more ethanol/amino acids. That could inform future...
The study links macrophage CD38-driven NAD depletion to intestinal inflammation and shows that restoring NAD or blocking CD38 reduced disease in experimental colitis—suggesting a new metabolic target for IBD therapies.
This trial tests a non‑invasive capsule that samples the small intestine directly to search for microbial or metabolite signatures linked to symptoms and disease. If successful, it could help researchers identify...
Understanding why some IBD ulcers fail to heal could help researchers develop better treatments or biomarkers to predict healing, which matters because mucosal healing reduces hospitalizations, surgeries, and cancer...
Timing of mesalamine might change how much drug reaches the colon, gut inflammation markers, and the microbiome — which could affect symptom control or monitoring for people with UC. This trial tests that idea in people...
A microbiome-targeted, food-grade supplement could offer a non-immunosuppressive option for people with mild-to-moderate ulcerative colitis who remain inflamed or want to delay immunosuppressive/biologic therapy. The...
This registry will gather real-world safety and effectiveness data on infliximab in Chinese children with moderate-to-severe Crohn's disease, which can help clinicians and families understand how the drug performs...
IUS offers a rapid, radiation-free way to detect active inflammation and common complications in IBD, which could improve initial ED assessment and reduce reliance on CT scans.
The study identifies CDK9 inhibition as a way to reduce IL‑6/STAT3 signaling and protect the colonic epithelial barrier in preclinical models, suggesting a potential new therapeutic approach for ulcerative colitis...
IBD and obstructive sleep apnea may influence each other through shared biological processes (barrier dysfunction, dysbiosis, immune activation, intermittent hypoxia), so understanding this could affect screening and...
OTC painkiller use is very common among people with IBD, and those with recent disease activity are more likely to use them frequently and to take them specifically for IBD-related pain. Knowing this can help clinicians...
Viruses in the gut (including bacteriophages) could influence inflammation and the intestinal barrier in IBD, so understanding the virome may point to new research directions or therapies.
The work suggests specific host genes and cell types that might mediate links between gut microbes and IBD, which could direct future laboratory research into mechanisms and potential biomarkers.
Based on the title and source metadata, this appears to be a basic science related to Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of Radiation...
Shorter hospital stay after colorectal surgery can reduce disruption, infection risk, and costs. This review suggests ERAS pathways can shorten length of stay for people with IBD without increasing short-term...
Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...
This case series points to risankizumab as a potential option for children with IBD who have failed multiple biologics, and it reports use of noninvasive monitoring like intestinal ultrasound.
Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease and Complications. The original article is from Inflammatory bowel diseases.
The article reports a new oral nanozyme that combines imaging and ROS-scavenging therapy aimed at IBD lesions—an early-stage approach that could one day enable targeted, noninvasive treatment and lesion tracking.
Children with Crohn's and their clinicians often need noninvasive, accessible ways to monitor small-bowel disease. If validated elsewhere, IUS with the reported BWT thresholds could reduce reliance on MRE, which is...
