Article Archive

Page 21 of 100 · 4765 patient-friendly summaries

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.
Mymensingh medical journal : MMJ

Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.

Quality of life is often substantially affected in IBD; this study identifies active disease, greater severity, prior surgery, and stricturing Crohn's disease as factors linked to lower HRQoL, highlighting areas...

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Engineering a Built-in Piezoelectric Electron Sponge in Swallow Nanozyme for Inflammatory Bowel Disease Therapy.
Small (Weinheim an der Bergstrasse, Germany)

Engineering a Built-in Piezoelectric Electron Sponge in Swallow Nanozyme for Inflammatory Bowel Disease Therapy.

The article reports a new oral nanozyme that combines imaging and ROS-scavenging therapy aimed at IBD lesions—an early-stage approach that could one day enable targeted, noninvasive treatment and lesion tracking.

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Intestinal ultrasound versus magnetic resonance enterography for detecting small bowel Crohn's disease in children.
Journal of pediatric gastroenterology and nutrition

Intestinal ultrasound versus magnetic resonance enterography for detecting small bowel Crohn's disease in children.

Children with Crohn's and their clinicians often need noninvasive, accessible ways to monitor small-bowel disease. If validated elsewhere, IUS with the reported BWT thresholds could reduce reliance on MRE, which is...

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Anti-inflammatory activity of Chlorella polysaccharide AHP.
Molecular and cellular biochemistry

Anti-inflammatory activity of Chlorella polysaccharide AHP.

The study reports that Chlorella-derived polysaccharide AHP reduced inflammation, supported barrier repair, and changed gut microbiota in cell and mouse colitis models—suggesting a potential new bioactive candidate for...

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Beyond bowel wall thickness: Is the international bowel ultrasound segmental activity score ready for prime time in Crohn's disease?
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology

Beyond bowel wall thickness: Is the international bowel ultrasound segmental activity score ready for prime time in Crohn's disease?

Based on the title and source metadata, this appears to be an opinion or commentary related to Crohn's disease, Inflammatory bowel disease, and Intestinal ultrasound. The original article is from Indian journal of...

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Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea
Journal of Pharmacoepidemiology and Risk Management

Burden of Mental Disorders and Related Factors in Pediatric Patients with Ulcerative Colitis in Korea

This paper suggests children and teens with ulcerative colitis have higher rates of diagnosed mental disorders and antidepressant use compared with peers, indicating mental-health needs are an important part of pediatric...

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Synbiotics administration leads to attenuated mucosal inflammatory neutrophil infiltration and increased hematocrit in experimental ulcerative colitis
Cirugía y Cirujanos (English Edition)

Synbiotics administration leads to attenuated mucosal inflammatory neutrophil infiltration and increased hematocrit in experimental ulcerative colitis

Cure8 could only read part of this source from Cirugía y Cirujanos (English Edition), so this card uses cautious topic tags instead of a full summary. It is tagged for Ulcerative colitis, Inflammatory bowel disease, and...

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Advanced endoscopy and artificial intelligence-enabled vascular healing for ulcerative colitis: promising frontiers or mere mirage?
Clinical Endoscopy

Advanced endoscopy and artificial intelligence-enabled vascular healing for ulcerative colitis: promising frontiers or mere mirage?

If validated, AI-enhanced vascular assessment during endoscopy could give clearer, more reproducible information about mucosal and histologic healing — which matters for monitoring disease activity and guiding treatment...

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Upadacitinib Is Associated with the Lowest Risk of Treatment Failure Among Advanced Therapies for Ulcerative Colitis: A Real-World Administrative Claims Study.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Upadacitinib Is Associated with the Lowest Risk of Treatment Failure Among Advanced Therapies for Ulcerative Colitis: A Real-World Administrative Claims Study.

This large real-world study found upadacitinib was associated with lower risk of treatment failure and more corticosteroid-free stability compared with several other advanced therapies for ulcerative colitis —...

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Low Phase angle is a marker of deteriorated nutritional status and indicates a more active and endoscopically severe inflammatory bowel disease.
Clinical nutrition ESPEN

Low Phase angle is a marker of deteriorated nutritional status and indicates a more active and endoscopically severe inflammatory bowel disease.

Phase angle, an easy-to-measure BIA parameter, was lower in IBD patients with malnutrition and higher disease activity. Detecting malnutrition earlier could matter for patients' strength, healing, and overall outcomes.

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A bioactive lysate of Corynebacterium glutamicum orchestrates intestinal barrier repair mainly through L-arginine-mediated FOXO pathway.
Food research international (Ottawa, Ont.)

A bioactive lysate of Corynebacterium glutamicum orchestrates intestinal barrier repair mainly through L-arginine-mediated FOXO pathway.

The study suggests a bacterial lysate and L-arginine can restore intestinal barrier function in cell and mouse models — a process that could be relevant to IBD because barrier dysfunction contributes to disease activity.

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Drug Induced Myelosuppression and Alopecia Totalis in Ulcerative Colitis Patient: Unmasking the Enigma
Open Access Journal of Pharmaceutical Sciences and Drugs

Drug Induced Myelosuppression and Alopecia Totalis in Ulcerative Colitis Patient: Unmasking the Enigma

The report highlights a serious drug-related complication (pancytopenia/myelosuppression and hair loss) in a patient treated with azathioprine plus sulfasalazine for ulcerative colitis, suggesting clinicians and patients...

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Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.
European journal of pediatrics

Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.

Children with IBD and their caregivers may be interested in subcutaneous infliximab as an alternative to regular IV infusions because this review suggests it can maintain drug levels and remission after switching, with...

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AI-generated guidance for non-specialist physicians managing inflammatory bowel disease: expert evaluation and case-based testing of GPT-4 and DeepSeek.
Digestion

AI-generated guidance for non-specialist physicians managing inflammatory bowel disease: expert evaluation and case-based testing of GPT-4 and DeepSeek.

Non-specialist physicians often manage IBD where specialists are scarce. If reliable, AI tools could improve non-specialists' clinical reasoning and decision-making for IBD care.

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Bayesian Inference of Differential Metabolic Fluxes in Ulcerative Colitis using High-throughput Transcriptomics Data
Open Engineering Inc

Bayesian Inference of Differential Metabolic Fluxes in Ulcerative Colitis using High-throughput Transcriptomics Data

New computational tools that tie gene-expression to metabolic flux could help researchers identify metabolic pathways or biomarkers linked to ulcerative colitis, which might eventually inform research on disease...

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Nanoencapsulated flavonoids for inflammatory bowel disease: a targeted approach toward clinical application
npj Science of Food

Nanoencapsulated flavonoids for inflammatory bowel disease: a targeted approach toward clinical application

Nanoencapsulated flavonoids are proposed as a way to improve delivery of biologically active dietary compounds to the inflamed gut in IBD; a rational design framework could accelerate translation from bench research to...

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Differential Enteric Glial and Mast Cell Characteristics Distinguish Microscopic Colitis Subtypes Relative to Healthy and Disease Controls, with Treatment-Associated Reductions in Glial Reactivity and Mast Cell Degranulation in Collagenous Colitis
Cells

Differential Enteric Glial and Mast Cell Characteristics Distinguish Microscopic Colitis Subtypes Relative to Healthy and Disease Controls, with Treatment-Associated Reductions in Glial Reactivity and Mast Cell Degranulation in Collagenous Colitis

The paper identifies subtype-specific changes in enteric glial cells and mast cell activity in microscopic colitis and shows some treatment-associated reductions after budesonide; that helps explain disease biology and...

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No Independent Association Between Serum Zinc Levels and Endoscopic Disease Activity Assessed by the Ulcerative Colitis Endoscopic Index of Severity: A Single-Center Retrospective Study
GE - Portuguese Journal of Gastroenterology

No Independent Association Between Serum Zinc Levels and Endoscopic Disease Activity Assessed by the Ulcerative Colitis Endoscopic Index of Severity: A Single-Center Retrospective Study

The study suggests that serum zinc by itself may not be a reliable indicator of endoscopic inflammation in UC; nutritional status and inflammation (for example albumin and CRP) can confound zinc levels.

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Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.
Minerva gastroenterology

Influencing factors of health-related productivity loss among patients with inflammatory bowel disease in paid employment based on the theory of social ecosystem: a mixed-methods study.

Work-related productivity loss was common in this study and linked to both clinical (disease activity, strictures, fatigue) and psychosocial factors (anxiety, depression, self-efficacy, social support).

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Decoding Personalized Nutritional, Microbiome and Host Patterns Impacting Clinical and Prognostic Features in Crohn's Disease
ClinicalTrials.gov

Decoding Personalized Nutritional, Microbiome and Host Patterns Impacting Clinical and Prognostic Features in Crohn's Disease

Understanding how individual diet and microbiome patterns relate to disease activity could help create personalized dietary approaches for children with Crohn's disease and improve monitoring using home fecal...

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A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
ClinicalTrials.gov

A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis

This trial investigates a new oral medication (PALI-2108) for moderate-to-severe ulcerative colitis and could expand treatment options if later trials show benefit and safety. The study focuses on clinical remission at...

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Clinical utility of serum leucine-rich alpha-2 glycoprotein for assessing disease activity and mucosal healing in ulcerative colitis across different treatment settings: a prospective observational cohort study
BMC Gastroenterology

Clinical utility of serum leucine-rich alpha-2 glycoprotein for assessing disease activity and mucosal healing in ulcerative colitis across different treatment settings: a prospective observational cohort study

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Tests and monitoring. The original article is from BMC Gastroenterology.

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Stratified by baseline corticosteroid use: which advanced therapy works best for whom in ulcerative colitis?
Frontiers in Medicine

Stratified by baseline corticosteroid use: which advanced therapy works best for whom in ulcerative colitis?

The review suggests baseline corticosteroid use may change how well some advanced UC therapies work, especially IL-23 inhibitors and S1P modulators, which could affect treatment choices and trial reporting.

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Efficacy and Safety of Mirikizumab for Induction and Maintenance of Remission in Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Journal of Enterocolitis

Efficacy and Safety of Mirikizumab for Induction and Maintenance of Remission in Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Mirikizumab showed higher rates of clinical and endoscopic remission than placebo in pooled randomized trials, which could expand treatment options for people with moderate-to-severe ulcerative colitis if confirmed by...

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Probiotic Intervention With Bacillus coagulans and Lactobacillus acidophilus in Small Animals Experimental Ulcerative Colitis: Insights From a Small Animal Model
Veterinary Medicine and Science

Probiotic Intervention With Bacillus coagulans and Lactobacillus acidophilus in Small Animals Experimental Ulcerative Colitis: Insights From a Small Animal Model

An animal study found two probiotic strains reduced inflammation and inflammasome markers in an experimental ulcerative colitis model, which could inform veterinary treatments and early-stage research relevant to IBD.

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Transient Elastography for Liver Fibrosis and Steatosis in Inflammatory Bowel Disease: Current Evidence, Clinical Implications, and Future Directions
Journal of Enterocolitis

Transient Elastography for Liver Fibrosis and Steatosis in Inflammatory Bowel Disease: Current Evidence, Clinical Implications, and Future Directions

FibroScan detects liver fibrosis and steatosis that are common and sometimes under-recognized in people with IBD; identifying liver disease earlier could change monitoring or referral decisions, especially for patients...

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