Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 37 of 88 · 4205 articles
This preclinical study suggests that a specific gut microbe (Bacteroides acidifaciens) and the bile acid UDCA can reduce inflammation in a mouse colitis model by improving barrier function and dampening NLRP3-driven...
First-person stories show the real-life impact of Crohn’s: unpredictable flares, surgeries (including ileostomy), and long recovery can affect education, work, and mental health. Hearing recovery and remission are...
People with chronic colitis/IBD have higher rates of cardiovascular disease. This mouse study identifies a gut microbiota → immune cell → cardiac pathway (TLR4–GBP1) that might explain that link and point to future...
Identifying baseline cellular states that predict disease course or response to anti‑TNF could help researchers develop predictive biomarkers and new therapeutic strategies for pediatric Crohn’s disease.
Accurate recognition and standardized reporting of IBD-associated dysplasia help guide surveillance and surgical decisions because some dysplastic variants are flat, endoscopically invisible, and linked to advanced or...
Treatment resistance is a major hurdle in IBD care; this review maps how microbiota, immune imbalance, and epigenetics may work together to cause drug-resistant disease and suggests potential precision strategies that...
IBD patients sometimes have low iron or zinc and may try supplements. This trial tested whether two phytase-containing dietary supplements are acceptable and whether they change iron and zinc absorption in adults with...
A new oral drug, LMT503, is entering first-in-human testing for people with Crohn's disease and ulcerative colitis. Early-phase trials establish safety and how the body handles a drug—important first steps before any...
This narrative review surveys novel biomarkers and therapeutic strategies for adult IBD, topics that could affect diagnosis, monitoring, and future treatment options for people with Crohn's disease or ulcerative colitis.
Microbiome-based treatments target inflammation and microbial balance — central issues in IBD — and could offer new therapeutic options. This review collates clinical and mechanistic evidence but warns that results are...
JAK inhibitors are used to treat IBD and act broadly on immune signalling; understanding their cell-specific effects may explain who benefits, who doesn’t, and why adverse effects occur. This is directly relevant to...
The review found higher ultra-processed food intake was linked to increased odds of Crohn’s disease relapse — a potentially actionable signal because diet can be changed. However, the evidence certainty is very low, so...
Mental health symptoms are common in people with IBD and may be influenced by both psychological and biological factors. A virtual, group psychotherapy program tailored to IBD could increase access to treatment and help...
Sleep timing and morning light are modifiable, nonpharmacologic factors that could influence IBD quality of life and symptoms. If effective, a simple at-home light therapy could be an accessible adjunct to usual care.
This registry entry describes a completed Phase 2 study of a new IV drug (tulisokibart) for moderate–severe ulcerative colitis, including safety endpoints and a companion diagnostic — information patients may want when...
This trial tests a novel cell-derived extracellular vesicle therapy (DB-3Q) for people with Crohn’s disease who have not responded to standard advanced therapies. It may offer a different biologic approach if proven safe...
This observational study aims to link nutritional status and the dietary inflammatory potential to IBD activity and to test whether simple blood-derived inflammatory indices can serve as noninvasive markers of disease...
This study looks at how immunomodulators are actually used with biologic drugs in real-world practice when a national reimbursement policy forces biologic interruptions.
If you or someone you care for is not responding to anti‑TNF drugs for ulcerative colitis, this review explains biological reasons why that may happen and points toward research directions that could lead to better tests...
Researchers are investigating circRNAs as potential biomarkers and therapeutic targets in IBD because they may help explain disease mechanisms and lead to better diagnostics or treatments in the future.
Depressive symptoms during remission were associated with worse long-term physical, mental, and disease-specific quality of life, so attending to mental health can matter for overall wellbeing in IBD.
Growth impairment is a key concern in pediatric Crohn's disease; knowing which children are more likely to regain weight or height and how treatments like infliximab relate to growth can affect monitoring and treatment...
The study outlines a strategy to target corticosteroids to inflamed intestinal tissue by exploiting PLA2 overexpression, which could reduce systemic steroid side effects if the approach translates to biological models...
The review presents an emerging nanotechnology (TCM-derived carbon-dot nanozymes) that could offer new multitarget anti-inflammatory and antioxidant approaches for IBD, addressing limitations of current therapies and...
Researchers identified potential anti‑inflammatory mechanisms in a multi‑component herbal formula relevant to IBD pathways (NF‑κB, IL‑17) and showed in vitro reduction of pro‑inflammatory cytokines, which could guide...
Patient-derived intestinal organoids offer a human-relevant platform that could improve understanding of pediatric IBD biology and help predict individual treatment responses — potentially reducing trial-and-error...
Anaemia is a common and impactful complication in children diagnosed with IBD; knowing how often it occurs, which subtypes are most frequent, and its link with disease activity can guide monitoring and management...
This review directly compares surgery-first versus biologic-first strategies for localized ileocaecal Crohn's disease and suggests early resection can lower later treatment needs and leave some patients off medication,...
Imaging and endoscopy can give different pictures of disease activity in newly diagnosed pediatric Crohn’s disease. That matters because treatment decisions often rely on how active disease appears and where it’s...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Diet and lifestyle. The original article is from Food and Chemical Toxicology.
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Pharmacological...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Sensors and Actuators...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Microbiome. The original article is from Phytomedicine.
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Fitoterapia.
This mouse study suggests that acute colitis can alter liver immune responses—reducing CD8 T cells and shifting macrophages toward an anti-inflammatory M2 state—which may affect autoimmune cholangitis. That connection...
People with ulcerative colitis may be interested because the study identifies a botanical extract (Cortex Phellodendri alkaloids) that reduced disease in a mouse model and restored intestinal barrier markers, suggesting...
People with UC may care because the study identifies a compound and a signaling pathway that lowered inflammation and tissue injury in a commonly used mouse model of colitis, suggesting potential future therapeutic...
This review highlights probiotic and synbiotic approaches centered on L. plantarum that aim to rebalance gut microbiota and support the intestinal barrier—areas of direct interest to people with IBD seeking adjunctive,...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from International...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from International...
This study points to a plant-derived compound (Astragalus polysaccharides) that reduced colitis severity in a rat model by interfering with HMGB1/TLR4-driven neutrophil extracellular trap formation—pathways implicated in...
Cure8 found this source from Minerva gastroenterology, but the page could not be read reliably yet. It is tagged for Inflammatory bowel disease and Community and awareness. Open the original article for the full details.
Self-management and nursing-led psychoeducation may improve quality of life and reduce depressive symptoms for people with IBD. Family support appears to influence who benefits most, which could help tailor care.
Spiritual and existential concerns can affect coping and quality of life for people with IBD, but these needs are rarely assessed systematically. Validated, culturally adapted questionnaires could help clinicians and...
Digital health tools could offer more continuous monitoring and self-management support for people with IBD, potentially helping detect flares earlier and improve quality of life. This review collects existing evidence...
The study maps cell-level programs in ileum and colon that associate with failure to respond to biologic therapies, suggesting specific cellular markers and niches that could help explain treatment resistance and guide...
