Condition

Inflammatory bowel disease

Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.

Page 36 of 88 · 4205 articles

Sweet tea polysaccharides alleviate inflammation and regulate intestinal homeostasis via the gut-liver axis in ulcerative colitis mice
Journal of Functional Foods

Sweet tea polysaccharides alleviate inflammation and regulate intestinal homeostasis via the gut-liver axis in ulcerative colitis mice

Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Diet and lifestyle. The original article is from Journal of Functional Foods.

Read Summary
Prevalence of type 2 multimorbidities in COPD compared to asthma and relationship to blood eosinophilic counts.
ERJ open research

Prevalence of type 2 multimorbidities in COPD compared to asthma and relationship to blood eosinophilic counts.

People with COPD can have coexisting type‑2 inflammatory conditions, and those conditions become more common with higher blood eosinophil counts. Knowing this may influence clinicians’ attention to extra‑pulmonary T2...

Read Summary
Protease-serpin-microbiome interactions in inflammatory bowel disease: toward integrated biomarkers of gut health.
Gut microbes

Protease-serpin-microbiome interactions in inflammatory bowel disease: toward integrated biomarkers of gut health.

Protease and serpin activity affect the gut barrier, immunity, and microbial ecology—processes central to IBD. Integrating these pathways could help identify biomarkers or targets that explain why IBD varies between...

Read Summary
Preventive Effects of Fermented Yak Milk-Derived Lacticaseibacillus paracasei CD12-1 Against DSS-Induced Colitis in Mice
Foods

Preventive Effects of Fermented Yak Milk-Derived Lacticaseibacillus paracasei CD12-1 Against DSS-Induced Colitis in Mice

Preclinical results suggest a fermented yak milk–derived probiotic strain may protect against colitis in mice by improving barrier function, lowering inflammatory cytokines, and changing the gut microbiome—mechanisms...

Read Summary
Predictors of time to surgical recurrence after ileal or ileocolonic resection in Crohn’s disease: role of integrin αvβ6 and development of a predictive nomogram
Updates in Surgery

Predictors of time to surgical recurrence after ileal or ileocolonic resection in Crohn’s disease: role of integrin αvβ6 and development of a predictive nomogram

People with Crohn’s who have had ileal or ileocolic surgery often worry about needing another operation; this study seeks clinical and biomarker predictors to estimate that risk. Understanding predictors could help...

Read Summary
Bacillus Probiotic Spores in Supporting the Treatment of Chronic Inflammatory Bowel Disease
ClinicalTrials.gov

Bacillus Probiotic Spores in Supporting the Treatment of Chronic Inflammatory Bowel Disease

Patients and clinicians often seek adjunctive options to improve symptoms, quality of life, or reduce treatment burden. This trial tests whether Bacillus spore probiotics added to standard care can provide measurable...

Read Summary
Accurately Profiling the Changes and Functions of Key Microflora in the Whole Intestinal Microenvironment Based on the Visual Sampling Capsule Endoscopy in Patients With Inflammatory Bowel Disease
ClinicalTrials.gov

Accurately Profiling the Changes and Functions of Key Microflora in the Whole Intestinal Microenvironment Based on the Visual Sampling Capsule Endoscopy in Patients With Inflammatory Bowel Disease

Mapping microbes and metabolites directly from different gut regions could reveal location-specific changes linked to IBD activity and help researchers develop better biomarkers or targeted treatments.

Read Summary
Comparison Between Artificial Intelligence and Standard Reading to Investigate Suspected Crohn Disease: the SCAI STUDY
ClinicalTrials.gov

Comparison Between Artificial Intelligence and Standard Reading to Investigate Suspected Crohn Disease: the SCAI STUDY

Faster, reliable reading of capsule endoscopy videos could shorten diagnostic delays and make small-bowel evaluation easier for people with suspected Crohn’s disease. If AI preserves accuracy while reducing review time,...

Read Summary
Commentary on "Polyethylene terephthalate microplastics exposure enhances the risk of ulcerative colitis: insights from multiomics integration, machine learning, and molecular docking reveal intestinal toxicity mechanisms".
International journal of surgery (London, England)

Commentary on "Polyethylene terephthalate microplastics exposure enhances the risk of ulcerative colitis: insights from multiomics integration, machine learning, and molecular docking reveal intestinal toxicity mechanisms".

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and AI and data science. The original article is from International journal of surgery...

Read Summary
Intestinal Ultrasound Predicts Primary Non-Response and Maintenance Relapse in Upadacitinib-Treated Active Crohn's Disease: A Multicenter, Prospective Cohort Study.
Alimentary pharmacology & therapeutics

Intestinal Ultrasound Predicts Primary Non-Response and Maintenance Relapse in Upadacitinib-Treated Active Crohn's Disease: A Multicenter, Prospective Cohort Study.

If you or your clinician are using upadacitinib for Crohn’s, intestinal ultrasound early in treatment may help predict who will not respond and who is more likely to relapse on maintenance dosing, potentially guiding...

Read Summary
Calprotectin levels in Crohn's perianal fistula scraping are associated with fistula outcomes after surgical closure.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Calprotectin levels in Crohn's perianal fistula scraping are associated with fistula outcomes after surgical closure.

If confirmed, a simple calprotectin test on fistula scrapings could help predict which Crohn’s patients are likely to heal after primary surgical fistula closure and which may need additional therapies, potentially...

Read Summary
Microbiome-Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease.
MicrobiologyOpen

Microbiome-Derived Tryptophan Metabolites Regulate AhR Signaling to Restore Epithelial Barrier Integrity in Inflammatory Bowel Disease.

Microbial tryptophan metabolites may help restore the intestinal barrier via AhR signaling, a process that could reduce inflammation and symptom-driving permeability in IBD. Understanding this pathway could point to...

Read Summary
Ultrasound criteria for transmural healing and response in Crohn’s disease: a systematic review of definitions and thresholds
PubMed Central

Ultrasound criteria for transmural healing and response in Crohn’s disease: a systematic review of definitions and thresholds

Clear, reproducible ultrasound definitions for transmural healing and response could help clinicians track deeper intestinal healing beyond mucosal assessment and allow trials to use consistent imaging endpoints.

Read Summary
Nitrogen dioxide exposure promotes CD8+T cell infiltration and contributes to increased susceptibility to ulcerative colitis: An integrative multi‑omics, artificial intelligence, and mouse model study.
Journal of hazardous materials

Nitrogen dioxide exposure promotes CD8+T cell infiltration and contributes to increased susceptibility to ulcerative colitis: An integrative multi‑omics, artificial intelligence, and mouse model study.

The study suggests that air pollutant NO2 may promote a perforin-producing CD8+ T cell response linked to colonic inflammation in UC and highlights CDC25B as a potential mechanistic link—information that could guide...

Read Summary
Complication Profiles Following Right-Sided Segmental Colectomy: A Comparative Retrospective Analysis of Crohn's Disease and Colon Cancer.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre

Complication Profiles Following Right-Sided Segmental Colectomy: A Comparative Retrospective Analysis of Crohn's Disease and Colon Cancer.

This study helps set expectations about short-term risks after right-sided segmental colectomy for Crohn's disease compared with colon cancer. Knowing that overall complication rates were similar but infections were more...

Read Summary
Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti-tumor necrosis factor alpha therapy in children.
Journal of pediatric gastroenterology and nutrition

Dual biologic therapy in inflammatory bowel disease, a retrospective cohort study of vedolizumab and anti-tumor necrosis factor alpha therapy in children.

This study reports that combining an anti-TNF-α drug with vedolizumab helped many children with IBD who failed single-biologic therapy achieve clinical, endoscopic, and histologic improvement. It also notes serious...

Read Summary
Unraveling the pleiotropic roles of the mTOR-glycolytic axis in ulcerative colitis: from immunometabolic dysregulation to mucosal barrier remodeling
Frontiers in Immunology

Unraveling the pleiotropic roles of the mTOR-glycolytic axis in ulcerative colitis: from immunometabolic dysregulation to mucosal barrier remodeling

The review highlights metabolic pathways (mTOR–glycolysis) that drive inflammation and barrier dysfunction in ulcerative colitis, which could point to new kinds of targeted therapies beyond current immunosuppressive...

Read Summary
Formulation of Dipotassium Glycyrrhizinate loaded PVA polymeric nanoparticles Attenuate DSS-Induced Ulcerative Colitis via Modulation of Oxidative Stress, NF-κB/HMGB1 Signaling, and Mucosal Repair
Journal of Drug Delivery Science and Technology

Formulation of Dipotassium Glycyrrhizinate loaded PVA polymeric nanoparticles Attenuate DSS-Induced Ulcerative Colitis via Modulation of Oxidative Stress, NF-κB/HMGB1 Signaling, and Mucosal Repair

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from Journal of Drug...

Read Summary
Genetic and Epidemiologic Studies on Crohn’s Disease in Patients from Djibouti: Relationship Between CARD15/NOD2 Gene Mutations and Clinical/Demographic Factors
Europe PMC

Genetic and Epidemiologic Studies on Crohn’s Disease in Patients from Djibouti: Relationship Between CARD15/NOD2 Gene Mutations and Clinical/Demographic Factors

This study explores genetic risk variants (NOD2/CARD15) and local environmental factors (khat use) among young adults with IBD in Djibouti — information that may help explain regional differences in Crohn’s disease and...

Read Summary
A genome catalog reveals the global landscape of the human gut archaeome and its relevance to inflammatory bowel disease
Europe PMC

A genome catalog reveals the global landscape of the human gut archaeome and its relevance to inflammatory bowel disease

The study expands the map of gut archaea and identifies archaeal species associated with IBD/UC, suggesting new microbial biomarkers and potential microbe–microbe interactions that might influence inflammation.

Read Summary
Regulated cell death in autoimmune diseases: molecular mechanisms and therapeutic opportunities.
Molecular biology reports

Regulated cell death in autoimmune diseases: molecular mechanisms and therapeutic opportunities.

If you have IBD, emerging forms of regulated cell death may help explain ongoing intestinal inflammation and could become targets for future tests or treatments. This review highlights multiple RCD pathways linked to...

Read Summary
Probiotics Accelerate Microbiota and Metabolic Pathway Recovery Following Colonoscopy Bowel Preparation in Ulcerative Colitis.
Medical science monitor : international medical journal of experimental and clinical research

Probiotics Accelerate Microbiota and Metabolic Pathway Recovery Following Colonoscopy Bowel Preparation in Ulcerative Colitis.

People with UC have lower baseline gut microbial diversity and slower recovery after PEG bowel preparation; improving recovery of beneficial microbes could matter for symptom stability and gut health. This study suggests...

Read Summary
Tryptophan metabolism and AhR activation are associated with fecal water-induced DNA damage in patients with inflammatory bowel disease.
Mutagenesis

Tryptophan metabolism and AhR activation are associated with fecal water-induced DNA damage in patients with inflammatory bowel disease.

Altered tryptophan metabolism and AhR signaling were linked to fecal-water-induced DNA damage in IBD samples, suggesting a possible pathway connecting inflammation and epithelial genotoxic stress — a mechanism relevant...

Read Summary
A Steroid-Sparing Combination Regimen of Low-Dose Atorvastatin and Reduced-Dose Prednisolone Maximizes Healing in Experimental Ulcerative Colitis
Springer Science and Business Media LLC

A Steroid-Sparing Combination Regimen of Low-Dose Atorvastatin and Reduced-Dose Prednisolone Maximizes Healing in Experimental Ulcerative Colitis

The study suggests a steroid‑sparing combination (low‑dose atorvastatin plus reduced prednisolone) may produce stronger anti‑inflammatory and antioxidant effects than either drug alone in an animal model of ulcerative...

Read Summary