Condition
Broader IBD news covering Crohn's disease, ulcerative colitis, research, treatments, monitoring, and patient care.
Page 35 of 88 · 4210 articles
This study builds a large, public single-cell map of the gut in Crohn’s disease that identifies cell types and gene programs linked to inflammation. That can help researchers find new drug targets and explain why some...
IBD patients sometimes use dietary strategies and supplements like curcumin for inflammation. This study describes a food-processing method that preserves curcumin activity and targets release to the intestine in lab...
People with IBD may experience cognitive symptoms; this preclinical study identifies specific quercetin glycosides that protected mice from colitis-related cognitive decline via gut microbiota and tryptophan metabolism...
Researchers identified a plant-derived molecule (oxypalmatine) that reduced inflammation in a mouse colitis model by blocking pro-inflammatory macrophage activity through the RAB8A–STAT1 pathway. This suggests a...
The study suggests that timing of eating (time-restricted feeding) may influence intestinal inflammation and gut microbiota in ways that could be relevant to IBD. If confirmed in humans, meal timing could be a low-cost...
A plant polysaccharide (PVP) reduced inflammation and preserved intestinal barrier proteins in a mouse model of ulcerative colitis, apparently by increasing a specific gut bacterium. This points to a microbiome-related...
A new IL-17A drug (vunakizumab) is reported to have triggered severe ulcerative colitis in one patient, suggesting clinicians and patients starting IL-17A inhibitors should watch for early gastrointestinal symptoms.
Researchers are working to link specific gut microbes and their metabolites to host molecular changes in ulcerative colitis. This study maps candidate microbe–metabolite–host gene connections that could point to new...
This real-world multicenter study provides short-term effectiveness and safety data for upadacitinib in a difficult-to-treat Crohn’s population in China, which may inform treatment decisions and risk discussions.
These methods could help researchers and clinicians better identify which treatments are likely to work for which patients by combining trials and EHR data, accounting for multiple outcomes and missing data — relevant to...
If you have Crohn’s disease, upper GI biopsies showing focally enhanced gastritis or focally active inflammation could support a diagnosis of upper GI involvement and are associated with other histologic findings like...
People with IBD already have a higher baseline risk of colorectal cancer. This study finds that having multiple first‑degree relatives with CRC adds the largest absolute additional risk, which could affect how...
The study identifies Piezo1 in intestinal epithelial cells as a potential driver of intestinal fibrosis in IBD via a stiffness → ROS → partial EMT pathway, and suggests targeting Piezo1 or ROS could reduce fibrosis in...
If confirmed, molecular or microbial markers found at surgery could help identify Crohn’s patients at higher risk of postoperative endoscopic recurrence and inform closer monitoring or preventative strategies after...
Non-invasive, portable tests that can track inflammation more frequently could help patients and clinicians monitor disease activity between clinic visits and guide treatment decisions without repeated invasive...
The study identifies osteopontin as a stromal-secreted protein elevated in IBD-derived colonic fibroblasts and shows it can restrain epithelial maturation in human colonic organoids, a mechanistic insight that could be...
Food choices can affect Crohn’s symptoms, flares, and nutritional health. A short self-assessment can help you decide whether to change your diet or seek professional nutrition support.
The findings suggest that early biologic and immunomodulator treatment may reduce the need for first surgery in Crohn's disease, which is directly relevant to treatment planning and expectations for people with IBD.
Switching biologics is a frequent and consequential decision in children with IBD; using TDM and a mechanism‑based approach can help choose whether to optimize, switch within class, or change drug class.
If you or a child had Kawasaki disease, this study suggests there may be a higher long-term chance of certain skin autoimmune conditions (psoriasis, vitiligo) but no clear increase in IBD or several other autoimmune...
Malnutrition was common and much more frequent during active Crohn’s disease in this South Asian cohort, which matters because poor nutritional status affects treatment tolerance, recovery, and quality of life.
Community support can make a big practical and emotional difference for people with IBD who face major surgery and medical bills. Human stories also help raise awareness about the everyday impact of Crohn’s disease on...
Dating and relationships raise specific emotional and practical questions for people with Crohn’s (disclosure, symptom management, medication side effects). This article offers real-world tips to help people navigate...
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Mental health and quality of life. The original article is from msn.com.
Mental health conditions (depression, anxiety, ADHD) appear to increase before and after IBD diagnosis, suggesting psychological care may be needed earlier in the diagnostic pathway and long term.
The study highlights a bacterial gene that helps adherent-invasive E. coli (AIEC) colonize the gut — a mechanism that has been linked to Crohn's disease. Understanding how AIEC colonizes could guide future research into...
The findings show earlier and more frequent use of imaging, endoscopic assessment, anti-TNF therapy, and seton placement for active perianal fistulizing Crohn’s disease over recent years — practices that may affect...
People with IBD are at higher risk for colorectal cancer; identifying stromal genes that track inflammation-driven EMT could help researchers find biomarkers or targets that explain how chronic inflammation promotes...
A blood test (serum REG3α) may help identify people at higher risk of developing complicated Crohn's disease years before diagnosis and predict progression in established disease, which could inform monitoring or early...
Patients with UC and their clinicians may encounter CMV on colon biopsy testing; this study suggests CMV detection is linked with higher mucosal inflammation and a less favorable long-term course, highlighting a...
Physical activity may be a modifiable factor that could improve fitness, inflammation, symptoms like fatigue, and quality of life in children with IBD. This trial will provide objective, randomized data relevant to...
Awareness events connect people with Crohn’s and ulcerative colitis to local resources, support networks, and advocacy efforts. They can raise visibility and reduce isolation for people living with IBD.
CAR-Treg and Treg-cell therapies aim to specifically suppress harmful gut inflammation and could offer a new treatment option for people whose IBD does not respond to current drugs. Right now this is early-stage work —...
Finding reliable blood biomarkers for ulcerative colitis activity could make monitoring disease flares easier and less dependent on invasive tests. NGAL and S100A12 rising with active disease suggests they might help...
Researchers identified licochalcone B as a compound that reduced inflammation and repaired gut barrier in a mouse colitis model by affecting PI3K/AKT signaling and purine metabolism. For people following IBD research,...
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Tests and monitoring. The original article is from msn.com.
This FDA drug-label update describes approved uses and safety warnings for tofacitinib, a JAK inhibitor used in immune-mediated diseases including ulcerative colitis. The boxed warnings highlight serious infection and...
Sarcopenia (loss of muscle mass/strength) was common among hospitalized adults with active UC and linked to inflammation, changes in blood metabolites (bile acids, acylcarnitines), and shifts in the gut microbiome.
The work highlights macrophage metabolic programs and specific genes that may help classify UC molecular subtypes and suggest candidate biomarkers or therapeutic targets related to macrophage-driven inflammation.
The work links a PD risk gene (LRRK2 G2019S) to increased intestinal NET formation and enteric α-synuclein in mouse colitis, suggesting a neutrophil-mediated inflammatory route by which gut inflammation and microbiota...
AIEC bacteria have been linked to Crohn’s disease; this study identifies a bacterial gene (rfaG) that helps AIEC express adhesins and colonize the gut in experimental models, which could point to future research paths...
If AJs and E-cadherin signaling influence intestinal inflammation, that could change how researchers think about IBD causes and point to new molecular targets for study.
The study links a common environmental chemical (BPA) to worse epithelial injury and inflammation in colitis models, highlighting a potential environmental contributor to IBD-relevant epithelial dysfunction and...
PSC — a serious bile-duct disease linked to IBD — was found on MRCP in about 1 in 10 people at IBD diagnosis, often without abnormal liver blood tests. Early radiological detection could affect monitoring and specialist...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease and Research and clinical trials. The original article is from fingerlakes1.com.
The study suggests that anti‑TNF treatment in IBD is associated with weaker and less cross‑reactive antibody and memory B‑cell responses after COVID‑19 booster vaccination, which may reduce durability of protection and...
Researchers used machine learning and molecular docking plus small animal tests to link a common plasticizer (DEP) with molecular changes seen in pediatric Crohn’s disease. This could point to environmental exposures...
This is the official FDA label text for dexamethasone, so it clarifies approved uses and gives practical dosing and tapering guidance. It explicitly names "regional enteritis and ulcerative colitis," which matters to...
