Nutrition, food, supplements, exercise, sleep, stress, and lifestyle research for Crohn's disease and IBD.
Page 10 of 24 · 1124 articles
Researchers are working to link specific gut microbes and their metabolites to host molecular changes in ulcerative colitis. This study maps candidate microbe–metabolite–host gene connections that could point to new...
The study identifies Piezo1 in intestinal epithelial cells as a potential driver of intestinal fibrosis in IBD via a stiffness → ROS → partial EMT pathway, and suggests targeting Piezo1 or ROS could reduce fibrosis in...
Non-invasive, portable tests that can track inflammation more frequently could help patients and clinicians monitor disease activity between clinic visits and guide treatment decisions without repeated invasive...
Food choices can affect Crohn’s symptoms, flares, and nutritional health. A short self-assessment can help you decide whether to change your diet or seek professional nutrition support.
Malnutrition was common and much more frequent during active Crohn’s disease in this South Asian cohort, which matters because poor nutritional status affects treatment tolerance, recovery, and quality of life.
Dating and relationships raise specific emotional and practical questions for people with Crohn’s (disclosure, symptom management, medication side effects). This article offers real-world tips to help people navigate...
Physical activity may be a modifiable factor that could improve fitness, inflammation, symptoms like fatigue, and quality of life in children with IBD. This trial will provide objective, randomized data relevant to...
Researchers identified licochalcone B as a compound that reduced inflammation and repaired gut barrier in a mouse colitis model by affecting PI3K/AKT signaling and purine metabolism. For people following IBD research,...
Sarcopenia (loss of muscle mass/strength) was common among hospitalized adults with active UC and linked to inflammation, changes in blood metabolites (bile acids, acylcarnitines), and shifts in the gut microbiome.
Researchers used machine learning and molecular docking plus small animal tests to link a common plasticizer (DEP) with molecular changes seen in pediatric Crohn’s disease. This could point to environmental exposures...
Herpes zoster is more common and can be more severe in people with IBD, especially those on certain immunosuppressive drugs. Understanding therapy-specific risks and vaccine options can help prevent painful...
Medication adherence affects how well IBD maintenance treatment works. This study highlights the everyday challenges and beliefs that shape whether people stick with prescribed therapies, which can help clinicians and...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Diet and lifestyle. The original article is from Journal of Functional Foods.
Many people with IBD change their diets and avoid foods they believe trigger flares. Differences between Crohn’s disease and ulcerative colitis were observed, and many—especially those with UC—reported not receiving...
Vitamin D deficiency is common in people with IBD and this study suggests correcting deficiency may help rebalance immune cells and the microbiome—potentially supporting inflammation control alongside standard...
Protease and serpin activity affect the gut barrier, immunity, and microbial ecology—processes central to IBD. Integrating these pathways could help identify biomarkers or targets that explain why IBD varies between...
Preclinical results suggest a fermented yak milk–derived probiotic strain may protect against colitis in mice by improving barrier function, lowering inflammatory cytokines, and changing the gut microbiome—mechanisms...
Patients and clinicians often seek adjunctive options to improve symptoms, quality of life, or reduce treatment burden. This trial tests whether Bacillus spore probiotics added to standard care can provide measurable...
Mapping microbes and metabolites directly from different gut regions could reveal location-specific changes linked to IBD activity and help researchers develop better biomarkers or targeted treatments.
Faster, reliable reading of capsule endoscopy videos could shorten diagnostic delays and make small-bowel evaluation easier for people with suspected Crohn’s disease. If AI preserves accuracy while reducing review time,...
Microbial tryptophan metabolites may help restore the intestinal barrier via AhR signaling, a process that could reduce inflammation and symptom-driving permeability in IBD. Understanding this pathway could point to...
The study suggests that in some people with IBD who have Candida overgrowth, systemic antifungal therapy (fluconazole) can change gut microbes and metabolites in ways linked to better disease activity over 8 weeks. That...
Nutrition support choices (enteral vs parenteral) can affect remission, healing, and complications in IBD, post-surgical recovery, and critical illness. Understanding current evidence helps patients and clinicians make...
The review highlights metabolic pathways (mTOR–glycolysis) that drive inflammation and barrier dysfunction in ulcerative colitis, which could point to new kinds of targeted therapies beyond current immunosuppressive...
This study explores genetic risk variants (NOD2/CARD15) and local environmental factors (khat use) among young adults with IBD in Djibouti — information that may help explain regional differences in Crohn’s disease and...
The study expands the map of gut archaea and identifies archaeal species associated with IBD/UC, suggesting new microbial biomarkers and potential microbe–microbe interactions that might influence inflammation.
People with UC have lower baseline gut microbial diversity and slower recovery after PEG bowel preparation; improving recovery of beneficial microbes could matter for symptom stability and gut health. This study suggests...
The study suggests a steroid‑sparing combination (low‑dose atorvastatin plus reduced prednisolone) may produce stronger anti‑inflammatory and antioxidant effects than either drug alone in an animal model of ulcerative...
This preclinical study suggests that a specific gut microbe (Bacteroides acidifaciens) and the bile acid UDCA can reduce inflammation in a mouse colitis model by improving barrier function and dampening NLRP3-driven...
First-person stories show the real-life impact of Crohn’s: unpredictable flares, surgeries (including ileostomy), and long recovery can affect education, work, and mental health. Hearing recovery and remission are...
Microbiome-based treatments target inflammation and microbial balance — central issues in IBD — and could offer new therapeutic options. This review collates clinical and mechanistic evidence but warns that results are...
The review found higher ultra-processed food intake was linked to increased odds of Crohn’s disease relapse — a potentially actionable signal because diet can be changed. However, the evidence certainty is very low, so...
Sleep timing and morning light are modifiable, nonpharmacologic factors that could influence IBD quality of life and symptoms. If effective, a simple at-home light therapy could be an accessible adjunct to usual care.
This observational study aims to link nutritional status and the dietary inflammatory potential to IBD activity and to test whether simple blood-derived inflammatory indices can serve as noninvasive markers of disease...
The study outlines a strategy to target corticosteroids to inflamed intestinal tissue by exploiting PLA2 overexpression, which could reduce systemic steroid side effects if the approach translates to biological models...
The review presents an emerging nanotechnology (TCM-derived carbon-dot nanozymes) that could offer new multitarget anti-inflammatory and antioxidant approaches for IBD, addressing limitations of current therapies and...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Diet and lifestyle. The original article is from Food and Chemical Toxicology.
People with UC may care because the study identifies a compound and a signaling pathway that lowered inflammation and tissue injury in a commonly used mouse model of colitis, suggesting potential future therapeutic...
This review highlights probiotic and synbiotic approaches centered on L. plantarum that aim to rebalance gut microbiota and support the intestinal barrier—areas of direct interest to people with IBD seeking adjunctive,...
Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, Inflammatory bowel disease, and Research and clinical trials. The original article is from International...
Digital health tools could offer more continuous monitoring and self-management support for people with IBD, potentially helping detect flares earlier and improve quality of life. This review collects existing evidence...
The study identifies distinct fecal bile acid signatures in CRC versus UC that might help develop noninvasive tests to distinguish malignancy from chronic inflammatory disease of the colon.
Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Diet and lifestyle. The original article is from msn.com.
The study provides a more rigorous, leakage-free machine-learning analysis of a major IBD microbiome cohort and proposes reproducible microbial and metabolic pathway candidates that could eventually help IBD diagnosis or...
The study explores breath VOCs as a possible noninvasive biomarker for IBD activity, which could offer easier, more acceptable monitoring than colonoscopy or stool tests.
Identifying common multimorbidity patterns and using machine learning to predict premature mortality could help health systems and clinicians prioritize integrated care for people with IBD, potentially improving outcomes...
Researchers are exploring plant-derived polyphenols as potential anti-inflammatory agents for IBD. This preclinical study suggests a Tsaoko Fructus extract reduced colitis in mice, altered the gut microbiome toward...
The letter highlights salidroside as a potential multi-target agent that could modulate neuro-immune interactions and protect the gut barrier — mechanisms relevant to ulcerative colitis. Patients and clinicians may see...
