Nutrition, food, supplements, exercise, sleep, stress, and lifestyle research for Crohn's disease and IBD.
Page 11 of 24 · 1124 articles
Distinguishing acute infectious gastroenteritis from new‑onset IBD can be clinically challenging. Faecal biomarkers that help tell these apart could speed correct diagnosis and treatment and avoid unnecessary...
Preclinical work identified a plant-root extract fraction that reduced inflammation and improved some gut-barrier and microbiome features in a mouse model of ulcerative colitis, which could guide future research into new...
Improving oral delivery and colon targeting of probiotics could make probiotic therapies more effective for ulcerative colitis by increasing survival through the gut and retention at inflamed sites. If translated to...
FABP2 is presented as a sensitive biomarker of intestinal mucosal injury and a possible contributor to IBD mechanisms; if validated, it could improve disease monitoring and suggest new therapeutic targets.
The review lays out a multidimensional precision-care model that could help make IBD treatment more personalized, reduce unnecessary continuous medication, and use biomarker and technology-driven adjustments to manage...
The study suggests that measuring fat-free mass (FFMI) may reveal nutritional recovery after an IBD flare that BMI alone misses, which matters for identifying and treating malnutrition in IBD.
The study identifies a new compound that reduced colitis severity in mice by acting on macrophage NF-κB signaling, lowering MMP7, improving epithelial barrier markers, and altering the gut microbiome — mechanisms...
The study suggests a plant-derived extract can reduce inflammation and help restore the intestinal epithelial barrier in laboratory models of ulcerative colitis, which is directly relevant to research into new IBD...
The study suggests that polyphenols can change gut bacteria and metabolite production differently in people with IBD versus healthy controls, which could matter for designing personalized dietary interventions.
This paper identifies a herbal formula that improved inflammation and epithelial barrier repair in a mouse colitis model and highlights specific molecular pathways (CAV1/FAK/paxillin and metabolite pathways) that might...
Different protein sources may affect IBD risk and relapses, especially for ulcerative colitis, and diet choices could be relevant to patients and clinicians managing IBD.
This mouse study suggests a blueberry-derived anthocyanin plus pectin complex can alter gut microbes and metabolites linked to inflammation, pointing to a dietary approach that might influence ulcerative colitis biology.
The review summarizes how extracellular vesicles (EVs) shape immune responses and barrier repair in the gut and discusses their potential as accessible biomarkers and as vehicles for precise IBD therapies — topics that...
A wearable sensor that reliably measures inflammation markers (CRP and calprotectin) from sweat could make inflammation monitoring less invasive and more frequent for people with IBD, potentially helping detect flares...
People with IBD may be interested because the article describes a potential new probiotic genus (Weissella) that has preclinical effects on inflammation and mucosal healing—areas relevant to managing flares and...
The review proposes a low-cost, non-immunosuppressive adjunctive strategy targeting the gut microbiome and luminal metabolism to help maintain remission in UC, an area of strong patient interest but limited clinical...
The study suggests that modifiable early-life factors (breastfeeding, diet, antibiotic exposure, etc.) may be linked to later IBD risk, especially Crohn's disease. That could inform future prevention research and...
Cure8 could only read part of this source from physiciansweekly.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Inflammatory bowel disease and Diet and lifestyle.
This study points to a plant-derived extract delivered in nanocarriers that reduced colon injury in a rat model of colitis, suggesting a potential route to targeted anti-inflammatory therapy that might avoid systemic...
Smoking is a known risk factor for Crohn’s recurrence after bowel surgery. This study suggests newer products marketed as potentially safer (HNBT and e-cigarettes) were also linked to higher postoperative endoscopic...
Researchers report a modest association between higher estimated dietary sodium and greater odds of several IL-17–mediated diseases, while IBD showed a small inverse association. Patients may be interested because it...
Researchers are exploring natural compounds that might reduce intestinal inflammation and rebalance the gut microbiome. If translatable to humans, such approaches could inform new treatments or adjunctive therapies for...
The review connects UC pathological features to specific drug-delivery design needs, which could guide development of therapies that reach and act effectively in inflamed colon tissue. For people with UC, better-targeted...
IBD can cause cognitive and neurological symptoms. This preclinical study suggests a flavonoid-rich Chrysanthemum extract reduced colitis and related cognitive deficits in mice by changing the gut microbiota and...
This trial tests a new oral live biotherapeutic designed to affect inflammation and the gut microbiome in Crohn’s disease. Early‑phase safety and pharmacodynamic results could influence future development of...
Sleep problems are common in Crohn’s disease and may worsen symptoms, pain, and inflammation. This trial is testing whether a remotely delivered insomnia treatment is feasible and whether improving sleep could also...
The study identifies a plant-derived compound (curcumol) that reduced inflammation, mucosal injury, and some microbiome/metabolome disturbances in a mouse model of ulcerative colitis and links these effects to...
Researchers are exploring new anti-inflammatory molecules for ulcerative colitis. Mechanistic data showing inhibition of macrophage M1 polarization, MAPK signaling, and antioxidant activity may help prioritize VpG for...
Butyrate supports intestinal health and is often low in IBD. A single oral compound that reliably restores luminal butyrate could — if proven safe and effective in humans — offer a new way to treat ulcerative colitis or...
This single case shows that bedside ultrasound can detect serious abdominal problems (intussusception, ischemia) early in people with IBD even when initial vitals and labs look normal.
Chronic pain is common in people with Crohn’s disease and ulcerative colitis and can persist despite controlling gut inflammation. Brief online pain-education programs could offer a low-burden, scalable way to reduce...
Researchers and clinicians are exploring fungi’s role in IBD beyond bacteria. For patients, seeing Candida in stool tests is usually a signal of microbiome disruption rather than proof of fungal infection that requires...
This preclinical study suggests Antarctic krill oil may reduce inflammation and alter the gut microbiome in a mouse model of ulcerative colitis, which could point toward microbiota-targeted nutritional strategies worth...
Fatigue is very common in people with IBD—even when the disease is in remission—and is linked with lower physical activity, more sitting time, and with anxiety/depression. Understanding these links may help patients and...
Environmental cadmium exposure may alter the gut microbiome’s metabolites (oleic acid) and worsen colitis in mice via FFAR4-linked inflammatory pathways. If similar mechanisms operate in people, this could point to new...
Eating disorders and GI diseases frequently overlap and can worsen nutrition, symptoms, and disease management; recognizing this overlap helps patients and clinicians avoid missed diagnoses and get integrated care.
Diet quality was linked to gut microbiome features and exploratory differences in inflammatory markers and symptoms in adults with Crohn disease from Puerto Rico; understanding these links may help tailor dietary...
People with IBD might be interested because the study explores a new natural-product intervention that appears to reduce colitis severity in an animal model by activating the Nrf2 antioxidant pathway — a pathway already...
Non-invasive, inexpensive blood-derived ratios could offer easier, more frequent assessment of IBD activity than repeat endoscopy. This study evaluates several such ratios (CAR, PAR, NLR, FAR, Hb/CRP) against clinical...
This trial tests whether a seaweed-derived fucoidan given with standard 5-ASA therapy can change biomarkers linked to mucosal healing (fecal calprotectin, fecal short-chain fatty acids) and stool consistency in people...
Researchers are exploring ferroptosis as a double-edged mechanism: preventing it may protect healthy gut lining in IBD, while inducing it might help treat colorectal cancer. Advances could lead to new biomarkers or...
The study suggests a fermented seed protein ingredient may reduce inflammation, oxidative stress, and microbiota imbalance in an experimental colitis model — mechanisms relevant to IBD. That could inform future dietary...
Research linking ETBF to intestinal inflammation and colorectal cancer suggests better detection and targeted therapies for this microbe could eventually affect IBD management and cancer risk assessment.
Nutrition during acute severe ulcerative colitis matters because patients can become rapidly nutritionally fragile, and appropriate feeding and monitoring can affect recovery, complications, and readiness for surgery....
The paper suggests gut bacteria make an anti-inflammatory metabolite (NOP) that accumulates in IBD and reduces inflammatory responses in cells and multiple mouse colitis models, pointing to a potential microbiome-derived...
Time-restricted eating could offer a nonpharmacologic way to improve weight and some metabolic measures, and an early small study suggests it might reduce some Crohn’s symptoms in people who are overweight and in...
The paper describes plant-derived compounds that reduced inflammation and partly corrected gut microbiome disturbances in lab and mouse models of colitis, suggesting a possible route to microbiome-targeted IBD therapies...
Delays in diagnosing IBD are common and can raise the risk of complications, so understanding when to push for testing matters. The article explains tests and differences between IBS and IBD to help people know when to...
