Colonoscopy, endoscopy, fecal calprotectin, CRP, imaging, intestinal ultrasound, and monitoring research.
Page 6 of 33 · 1559 articles
Rising IBD incidence and prevalence in Asia mean more people will need long-term care, specialist services, and health-system planning. Understanding regional trends helps patients and policymakers anticipate resource...
Cardiorespiratory fitness (VO2peak) is an important health measure and may be relevant for people with IBD. Having accurate, simpler ways to estimate VO2peak makes it easier to assess fitness in clinic or studies without...
Perianal fistulas cause significant morbidity and often need both medical and surgical treatments. Newer drug options and updated guideline support earlier use of advanced therapies, which may improve healing and reduce...
The study identifies an epithelial cell death signature (necroptosis then apoptosis) that appears before major inflammation and which correlated with relapse over 24–36 months, suggesting a possible early biomarker to...
Perianal fistulizing Crohn's often causes significant symptoms and requires both medical and surgical approaches. Newer biologics and JAK inhibitors expand treatment options and guidelines increasingly support earlier...
Extraintestinal problems are common in IBD and can cause significant symptoms and treatment needs beyond the bowel. Knowing their frequency helps patients and clinicians prioritize screening and multidisciplinary care.
A platform trial could evaluate multiple advanced therapies and combinations more efficiently, which matters for people with refractory Crohn's disease who have already tried several advanced treatments.
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Medications. The original article is from Crohn's & colitis 360.
A new chemiluminescent probe could help researchers see and measure MPO-driven HOCl inflammation deeper in tissues, which may speed preclinical testing of IBD therapies and biomarker development.
Identifying people at very early, preclinical stages of Crohn’s disease could allow enrollment in prevention trials and earlier intervention. Faecal calprotectin may help select higher‑risk first‑degree relatives for...
Detecting molecular signs of IBD before symptoms could eventually allow earlier monitoring or preventive strategies, changing how and when people at risk are identified. For patients, this research points to hope that...
This study gives real-world comparative data on two biologic options (vedolizumab vs anti-TNFα) used early in the treatment course for Crohn’s disease, which may help patients and clinicians weigh effectiveness and...
A subcutaneous option for infliximab could simplify maintenance therapy, reduce infusion visits, and change how drug levels and accompanying immunomodulators are managed — issues many people with IBD and their clinicians...
Patients and clinicians choosing among advanced therapies for ulcerative colitis may consider infection-related hospitalization risk as one factor; this study suggests lower risk with ustekinumab versus TNF antagonists...
The study suggests habitual diet that supports gut microbes may modestly lower the chance of developing IBD, especially ulcerative colitis, and links dietary patterns to blood protein changes tied to immune and...
Based on the title and source metadata, this appears to be a clinical study related to Ulcerative colitis, Inflammatory bowel disease, and Infliximab. The original article is from Inflammatory Bowel Diseases.
Predicting who will relapse after stopping anti-TNF drugs could help avoid unnecessary flares or unnecessary ongoing treatment. A biopsy-based transcriptomic test could be a useful decision tool if validated.
The paper points to S100A8 as a potential link between immune-cell-driven inflammation and mitochondrial stress in Crohn’s disease, which could help researchers explore new biomarkers or targets for study.
This is relevant because many younger women with iron deficiency anemia are considered for upper and lower endoscopy to find bleeding sources or other causes. The study shows common diagnostic codes recorded after...
Based on the title and source metadata, this appears to be a clinical study related to Inflammatory bowel disease, Vedolizumab, and Anti Integrin. The original article is from Journal of the Canadian Association of...
This study proposes three autophagy-related genes (APOL1, CCL2, IL24) as potential biomarkers that may help classify ulcerative colitis patients into subtypes with different immune environments, which could eventually...
People with ulcerative colitis face long-term health risks beyond the gut. This study suggests that getting a colectomy early after diagnosis might be linked to lower long-term risk of cardiovascular disease and type 2...
Children with newly diagnosed IBD are increasingly started on advanced therapies early after diagnosis and are receiving fewer corticosteroids.
The work highlights molecular differences between PSC-UC and typical UC that could help explain higher colorectal cancer risk in PSC-UC and suggests candidate miRNA biomarkers (eg, miR-155) for further study.
Relatives of people with IBD are at higher risk; this study aims to identify early markers or behaviors that predict who develops IBD so prevention or earlier diagnosis might become possible.
Patients and clinicians are often looking for objective, noninvasive ways to monitor IBD activity. This study suggests a simple nailfold capillary measure may reflect disease activity and add information to CRP, which...
The paper suggests a molecular link (RHBDF2–ADAM17–TNFα) between ulcerative colitis and blood–brain barrier disruption, which could explain some neurological comorbidities of UC and identify targets for future therapies.
This review summarises the rapidly changing drug landscape for Crohn’s disease and ulcerative colitis, including newly approved biologics and small molecules and several emerging therapies that may affect future...
Transmural healing on CT enterography was associated with fewer hospitalizations over long follow-up, which could matter for long-term disease management and monitoring strategies in Crohn’s disease.
Accurate, radiation-free imaging at the point of care can speed diagnosis and management of strictures, abscesses, and fistulas in Crohn’s disease. Improved ultrasound techniques may help determine who needs surgery or...
Small-bowel capsule and balloon-assisted endoscopy are increasingly used for Crohn’s disease; this large real-world study suggests adverse events after SBCE are uncommon and may be less frequent when a patency capsule is...
A reliable endoscopic method that matches histology could reduce the need for biopsies and speed decisions about remission and treatment in UC. Patients and clinicians interested in noninvasive, real‑time inflammation...
A pediatric trial of budesonide rectal foam could provide evidence about a locally acting steroid option for children with distal ulcerative colitis. Trial results may affect treatment choices for pediatric distal...
Based on the title and source metadata, this appears to be a clinical study related to Crohn's disease, Inflammatory bowel disease, and Fistula. The original article is from Journal of ultrasound in medicine : official...
If oxalate in certain plant foods can irritate inflamed intestines or be less well absorbed in IBD, eating large amounts could worsen symptoms for some patients. Awareness can help people track triggers rather than...
For people with Crohn’s disease, this study suggests that biologic drugs reduce inflammation in both proximal and distal small bowel to a similar degree, as measured by capsule endoscopy.
Abdominal tuberculosis can closely mimic Crohn’s disease and abdominal cancers, so recognizing radiological and microbiological approaches that improve diagnosis helps avoid misdiagnosis and unnecessary surgery,...
Microbiome patterns in this study were linked to inflammation (fecal calprotectin) and higher chance of needing treatment escalation. If validated, enterotype stratification could help predict disease course or tailor...
Patients and clinicians choosing a next biologic after prior biologic failure may find evidence here that effectiveness is broadly similar between vedolizumab and ustekinumab overall, with potential differences depending...
Persistent bowel symptoms can signal a range of conditions, including rare cancers; prompt evaluation helps ensure appropriate diagnosis and treatment. The story highlights symptom overlap between Crohn’s disease and...
If validated, mucosal biomarkers like SPARC and SPP1 might help predict who will not respond to infliximab, potentially guiding treatment choices and avoiding ineffective therapy for some people with UC.
The study describes real-world use of a treat-to-target approach in adults with Crohn's disease and ulcerative colitis, which may influence how clinicians monitor disease and adjust therapy in routine care.
Diet is a potentially modifiable factor that could affect symptoms, inflammation, and the gut microbiome in ulcerative colitis; this trial aims to test whether a modified Mediterranean diet added to standard therapy...
Bowel urgency is a common, distressing symptom in ulcerative colitis that matters for quality of life. This analysis indicates vedolizumab may reduce urgency and that early improvement is linked to better clinical and...
The study identifies a molecular epithelial program (GART-associated) linked to proliferation and purine metabolism in ulcerative colitis, which could inform future mechanistic research and biomarker development relevant...
The study identifies and functionally validates a new STXBP3 variant that likely causes VEOIBD with immunodeficiency, which can help explain disease in affected infants and inform genetic counseling and further research.
This project explores how CD74 in intestinal stem cells and Paneth cells helps control mucosal immune responses and epithelial repair — processes directly relevant to IBD pathogenesis and recovery.
People with IBD on biologic therapies may benefit from accurate drug-level testing to guide treatment decisions.
