Perianal fistulising Crohn's disease is hard to treat and often fails anti-TNF drugs. This study will provide real-world data on whether upadacitinib can be effective and safe for patients with refractory perianal...

Cure8 found this source from bioengineer.org, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Procedures and surgery. Open the original article for the full...

Supplements can worsen GI symptoms or interact with Crohn’s disease and its treatments. Knowing which products commonly cause problems can help avoid flares, masking of bleeding, or unnecessary side effects.

This study compares two commonly used biologics as first-line therapy for moderate-to-severe ulcerative colitis and reports better short- and long-term effectiveness for vedolizumab with similar safety. The results could...

Researchers used clustering on mixed clinical and treatment data to identify distinct Crohn's disease course trajectories and a small high-burden subgroup. If validated, such trajectories might help inform prognosis and...

Links between circulating adaptive receptors, coordinated immune programs, and short-term treatment-response signals could eventually enable blood-based immune biomarkers or patient stratification tools in IBD research...

Based on the title and source metadata, this appears to be a patient education related to Fistula and Procedures and surgery. The original article is from scirp.org.

Genetic testing can help identify both rare high-impact variants and a person’s polygenic risk, which may affect screening discussions and family risk awareness. For people with a family history or ancestry-related risk,...

The study suggests stromal fibroblasts can drive pro-inflammatory neutrophil programs in ulcerative colitis and that targeting fibroblast-associated pathways may reduce neutrophil-driven inflammation—information that...

Cure8 could only read part of this source from tradingview.com, so this card uses cautious topic tags instead of a full summary. It is tagged for Inflammatory bowel disease, Ulcerative colitis, and Crohn's disease.

A colon-targeted, enzyme-activated imaging probe could help distinguish early versus late inflammatory stages in IBD and provide a noninvasive fecal fluorescence signal—potentially improving disease monitoring beyond...

Depression before an IBD diagnosis was linked to more early treatment escalation and acute-care use after diagnosis. Recognizing preexisting depression could help clinicians identify patients who may benefit from closer...

The review highlights marine polysaccharides as multi-target agents that could modulate inflammation, the microbiome, and the gut barrier—processes central to ulcerative colitis—and points to possible roles as functional...

Cure8 found this source from app.dealroom.co, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. Open the original article for the...

A protein bar marketed for digestibility may appeal to people with Crohn’s, ulcerative colitis, or other IBD-related digestive sensitivity who struggle to find convenient, protein-rich snacks. The company’s community...

The study identifies a food-industry by-product (crayfish shells) as a source of peptides that reduced inflammation and improved barrier and antioxidant markers in cell and mouse colitis models—research that could inform...

Based on the title and source metadata, this appears to be a basic science related to Ulcerative colitis, AI and data science, and Research and clinical trials. The original article is from BMC Medical Research...

Many people with Crohn’s or colitis struggle to find convenient snacks that are easy to digest and provide protein. A company launching bars designed with digestibility in mind may be of practical interest to those...

Real-world registry data on upadacitinib can help patients and clinicians understand how the drug performs outside clinical trials, including patterns of use, effectiveness, and safety over time.

Identifies a fibroblast senescence signature and highlights ADAMTS2 as a candidate biomarker linked to inflammation and fibrosis in IBD, which could guide future diagnostic or therapeutic research relevant to Crohn’s...

This systematic review focuses on two ways surgeons reconnect the bowel after minimally invasive right-sided surgery for Crohn’s disease. It found fewer overall postoperative complications with intracorporeal anastomosis...

A simple blood lymphocyte percentage could be a convenient, non-invasive marker to help distinguish endoscopic remission from active disease in both Crohn’s and ulcerative colitis; chemokines CXCL10 and CCL25 may also...

People with Turner syndrome have higher rates of other autoimmune diseases; this case shows that celiac disease and ulcerative colitis can coexist and lead to growth and bone health problems.

The report explores NOD2/CARD15 variants in a Djiboutian IBD cohort and suggests higher variant frequencies in Crohn’s disease, which could point to population-specific genetic susceptibility. It also raises khat use as...

Postoperative recurrence is common after Crohn’s surgery; a reliable noninvasive test could reduce the need for early colonoscopy and help tailor follow-up.

Based on the title and source metadata, this appears to be a systematic review or meta analysis related to Inflammatory bowel disease and Research and clinical trials. The original article is from Indian Journal of...

Cure8 found this source from bioengineer.org, but the page could not be read reliably yet. It is tagged for Crohn's disease, Inflammatory bowel disease, and Research and clinical trials. Open the original article for the...

The paper links specific gut bacteria, inflammatory cytokines, and two microRNAs with UC activity, which could point toward new diagnostic biomarkers or targets for research into disease mechanisms.

Dietary macronutrients affect microbiota, barrier integrity, and mucosal immunity in ways that could alter IBD activity. Understanding these pathways could inform more targeted dietary strategies beyond generic...

Extracellular vesicle (EV) therapies are being explored as new ways to modulate immune responses and promote mucosal repair in IBD, which could eventually expand treatment options beyond current biologics and small...

Persistent diarrhea is a common, quality-of-life–limiting problem in ulcerative colitis; this review synthesizes how epithelial transport, barrier damage, immune signaling, mitochondria, and microbiota interact and...

People with IBD or their clinicians may worry that systemic antifungal treatment could trigger flares.

Non-invasive imaging biomarkers that track intestinal inflammation and structure could speed preclinical testing of IBD therapies and guide translational imaging research relevant to clinical monitoring of ulcerative...

This study compares two JAK inhibitors (upadacitinib and tofacitinib) used as rescue therapy for acute severe ulcerative colitis and reports lower 1‑year colectomy rates with upadacitinib. That could influence choices...

A direct-vision push-type dilator (BougieCap) was used to safely dilate a low rectal stricture from Crohn's disease, allowing same-session sigmoidoscopy and biopsy and reported symptom improvement up to 18 months.

Trial design affects how quickly and reliably new IBD treatments are tested and approved, and can influence patient experience (placebo exposure, retention) and whether trial populations reflect real-world patients.

The study documents substantial increases in Crohn’s disease and ulcerative colitis prevalence and changing incidence patterns in Northeastern Italy from 2012–2024, which may affect healthcare demand and resource...

Cure8 could only read part of this source from ground.news, so this card uses cautious topic tags instead of a full summary. It is tagged for Community and awareness.

If lymphatic dysfunction helps cause or sustain Crohn’s inflammation, it could explain some classic disease features (patchy, transmural inflammation and mesenteric changes) and point to new treatment approaches aimed at...

Identifying a genetic cause (XIAP frameshift variant) helped explain why anti‑TNF drugs failed and why blocking IL‑12/23 with ustekinumab led to improvement; that connection could influence treatment choices for similar...

Automated, validated grading of UC on colonoscopy images could reduce variability between endoscopists and help standardize severity assessment that influences treatment planning.

A reproducible animal model of perianal fistulizing Crohn’s disease could help researchers study how fistulas form and persist and provide a test platform for new therapies before human trials.

Regulatory approvals and trial activity for upadacitinib (Rinvoq) affect availability and prescribing patterns for immunomodulatory treatment options used across autoimmune and inflammatory diseases, including IBD.

Early prediction of who will not respond to infliximab could help clinicians avoid prolonged ineffective treatment, enabling earlier reassessment and changes in therapy as part of treat-to-target care.

Researchers have found a short peptide in potato protein with antioxidant and anti-inflammatory properties and are testing it as a possible oral treatment for intestinal inflammation — a potential new, plant-derived...

Based on the title and source metadata, this appears to be a patient education related to Crohn's disease, Inflammatory bowel disease, and Diet and lifestyle. The original article is from msn.com.

IL-23 inhibitors are a newer class of biologics for moderate-to-severe ulcerative colitis that may offer another effective option for patients who have not responded to existing therapies, with improving evidence for...

Patients and clinicians often need evidence about whether switching from ustekinumab to an anti‑TNF (infliximab or adalimumab) still gives meaningful clinical responses. This study suggests many patients can respond, but...